Additional file 2: of MicroRNA-31-5p regulates chemosensitivity by preventing the nuclear location of PARP1 in hepatocellular carcinoma

Figure S2. miR-31-5p affects the cisplatin content of specific organelles within the intracellular environment as well as oxaliplatin. (A) Isolation of the nuclear fraction following 1 mM cisplatin treatment for 24 h illustrated a trend toward increased cisplatin concentration with miR-31-5p reintroduction; however, this is a significant increase in Hep3B miR-31-5p and a decrease in Huh7 Zip-miR-31-5p (n = 5). (B)In carboplatin, there is a increase in Hep3B miR-31-5p, but this is not significant in Huh7 Zip-miR-31-5p (ns = not significant) (n = 5). Data are presented as the mean ± SEM. *p < 0.05; **p < 0.01. (TIF 2360 kb