Additional file 7: of Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome
- Antonella Tramutola (284818)
- Chiara Lanzillotta (5933198)
- Eugenio Barone (297203)
- Andrea Arena (5933201)
- Ilaria Zuliani (5933204)
- Luciana Mosca (83281)
- Carla Blarzino (328306)
- D. Butterfield (5933210)
- Marzia Perluigi (297205)
- Fabio Di Domenico (328312)
Publication date
November 2018
DOIAbstract
Immunofluorescence staining of Dentate gyrus in Eu and Ts65Dn mice. Representative immunofluorescent images showing (A) p-mTOR at serine 2448, (B) at Ser416 and (C) APP/Ab levels in the dentate gyrus region of the hippocampus from euploid mice treated with Veh and InRapa (A.1–4), and Ts65Dn mice treated with Veh and InRapa (A.5–8). DAPI (blue) was used to identify cell nuclei. Scale bar represent 20 μm. On the right of each panel a graph of the quantification of fluorescence signal is reported. (PPTX 16410 kb
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