Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition - Fig 6
- Dina Schneidman-Duhovny (10167)
- Natalia Khuri (1992196)
- Guang Qiang Dong (5937947)
- Michael B. Winter (2197576)
- Eric Shifrut (5937950)
- Nir Friedman (42607)
- Charles S. Craik (174573)
- Kathleen P. Pratt (411067)
- Pedro Paz (5937953)
- Fred Aswad (5937956)
- Andrej Sali (17326)
Publication date
November 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
A) Orientations of TCRs with respect to MHCII in the 20 benchmark complexes. B) Orientations of TCRs with respect to MHCII in the 500 template structures generated by docking. C) Distribution of RMSD values between the 20 benchmark pMHCII-TCR structures. D) Distribution of RMSD values between the 500 template structures. Addition of docking generated templates resulted in better coverage of orientation space as indicated by the smoother RMSD distribution on the right.</p
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