The effects of CX3CL1 on the gene expression of inflammatory mediators in WT mice-derived peritoneal macrophages.

WT mouse-derived peritoneal macrophages were incubated with the indicated concentrations of CX3CL1 for 3 h. RT-PCR was performed on the extracted total RNAs as described in Materials and Methods. The gene expression of Il1b (A), Il6 (B), Tnfa (C) and Ptgs2 (D) are shown. All values represent the mean ± SEM; Statistical significance determined using Mann-Whitney’s U test. *, P < 0.05; vs. no CX3CL1 treatment (n = 10 cases in each group).