Figure S3. Satellite cell numbers are increased in Gaa−/− TA muscle. The number of Pax7-positive cells in 15 week (A) and 25 week (B) WT and Gaa−/− from Fig. 3 expressed as Pax7-positive cells/myofiber. Data are means ± SD from 2 muscles derived from 2 different animals per genotype per timepoint. *p < 0.05 and **p < 0.01. (PDF 103 kb
Figure S3. The differentiation of myoblasts from ΔKlotho mice is not affected in vitro. (A) Quantifi...
Figure S7. Histological analysis of additional Pax7EGFP muscles. Representative images of quadriceps...
Figure S1. ΔKlotho mice display signs of sarcopenia. (A) Immunofluorescence of cross-sections of TA ...
Figure S5. Satellite cell numbers are increased in Gaa−/−(Bl6) muscle. A. Satellite cells were detec...
Figure S2. Modest muscle regeneration in Gaa−/−(Bl6) animals. A.eMyHC staining of QF sections from W...
Figure S6. Detection of proliferating satellite cells in GAA-deficient limb muscle. Representative i...
Figure S4. Identification of Pax7-positive satellite cells by flow cytometry. A. Representative dot ...
Figure S9. Efficient regeneration of GAAKO-muscle after cardiotoxin-induced injury in GAA-deficient ...
Figure S1. Reduced fiber diameter in GAAKO animals. A. Fiber diameter frequency distribution plot of...
Unchanged satellite cell proliferation in Pompe disease. Cryosections from Pompe muscle biopsies wer...
Examples of immunofluorescent Ki67 stainings. Left: Human tonsil was stained as positive control and...
Example of MyoD (red, arrow) and Myogenin (green, arrow) immunofluorescent stainings. These markers ...
Examples of muscle fibers that show evidence of recent muscle regeneration. The arrows point to cent...
Figure S2. Characterization of mouse primary satellite cells. (A) Undifferentiated SC at 60% conflue...
Average muscle fiber cross sectional area (CSA) is shifted rightward with a consistent distribution ...
Figure S3. The differentiation of myoblasts from ΔKlotho mice is not affected in vitro. (A) Quantifi...
Figure S7. Histological analysis of additional Pax7EGFP muscles. Representative images of quadriceps...
Figure S1. ΔKlotho mice display signs of sarcopenia. (A) Immunofluorescence of cross-sections of TA ...
Figure S5. Satellite cell numbers are increased in Gaa−/−(Bl6) muscle. A. Satellite cells were detec...
Figure S2. Modest muscle regeneration in Gaa−/−(Bl6) animals. A.eMyHC staining of QF sections from W...
Figure S6. Detection of proliferating satellite cells in GAA-deficient limb muscle. Representative i...
Figure S4. Identification of Pax7-positive satellite cells by flow cytometry. A. Representative dot ...
Figure S9. Efficient regeneration of GAAKO-muscle after cardiotoxin-induced injury in GAA-deficient ...
Figure S1. Reduced fiber diameter in GAAKO animals. A. Fiber diameter frequency distribution plot of...
Unchanged satellite cell proliferation in Pompe disease. Cryosections from Pompe muscle biopsies wer...
Examples of immunofluorescent Ki67 stainings. Left: Human tonsil was stained as positive control and...
Example of MyoD (red, arrow) and Myogenin (green, arrow) immunofluorescent stainings. These markers ...
Examples of muscle fibers that show evidence of recent muscle regeneration. The arrows point to cent...
Figure S2. Characterization of mouse primary satellite cells. (A) Undifferentiated SC at 60% conflue...
Average muscle fiber cross sectional area (CSA) is shifted rightward with a consistent distribution ...
Figure S3. The differentiation of myoblasts from ΔKlotho mice is not affected in vitro. (A) Quantifi...
Figure S7. Histological analysis of additional Pax7EGFP muscles. Representative images of quadriceps...
Figure S1. ΔKlotho mice display signs of sarcopenia. (A) Immunofluorescence of cross-sections of TA ...