Clonogenic potential of bone marrow myeloid progenitors.

Number of colony-forming units (CFU) and clusters in soft-agar culture of BM cells from: CY–CY-immunosuppressed mice; CY+Tarin—CY-immunosuppressed mice treated concomitantly with 200μg tarin on day 0; Tarin—mice treated with 200 μg tarin on the same day or Control—mice inoculated with saline. BM cells were collected on day 4 and plated with GM-CSF or G-CSF stimuli. Responses to GM-CSF (A) and to G-CSF (B) were analyzed on the 7th day. Results are expressed as the mean values and standard errors of three independent experiments. *pp<0.0001 compared to the control group.