Venn diagram of time-course metabolite changes between the comparisons of 1h 50GNPs vs. control and 3h 50GNPs vs. control.

Macrophages were exposed to 0 (control) or 50 μg/mL GNPs for 1 or 3h followed by metabolomics analysis. Identified metabolites with fold changes greater than 2 and p value less than 0.01 were are included within the diagram.