Mutations of common residue-wise determinants of structural dynamics between SII and α3 have similar effects in Ras, Gαt and EF-Tu.

Hongyang Li (296731)
Xin-Qiu Yao (85050)
Barry J. Grant (19471)

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Publication date

November 2018

DOI

10.1371/journal.pcbi.1006364.g005

Publisher

Public Library of Science (PLoS)

Abstract

Mutations M72ARas in SII (A) and V103ARas in α3 (D) significantly reduce the couplings between PL and SI. The counterpart mutations in Gαt and EF-Tu, F211AGαt in SII (B), F255AGαt in α3 (E), I93AEF-Tu in SII (C) and V126AEF-Tu in α3 (F) have similar effects in the nucleotide-binding region–significantly reducing the couplings between PL, SI and SII.</p

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Mutations of common residue-wise determinants of structural dynamics between SII and α3 have similar effects in Ras, Gαt and EF-Tu.

Abstract

Extracted data

Mutations of common residue-wise determinants of structural dynamics between SII and α3 have similar effects in Ras, Gαt and EF-Tu.

Abstract

Extracted data

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