Chromosome XII shows reduced nondisjunction in interspecific hybrids.

Chr XII exhibited a markedly lower nondisjunction rate than did other chromosomes in interspecific hybrids between S. cerevisiae strain Y55 and S. paradoxus strain N17 (data reproduced from Fig 2). We confirmed this result by examining the segregation of three chromosome pairs (I, VII, and XII) in crosses between S. cerevisiae strain Y55 and two other S. paradoxus strains from different clades: the American B strain YPS138 and the Far Eastern strain N44, as well as a cross between S. paradoxus strain N17 and a second S. cerevisiae strain, the laboratory model S288C. Underlying data can be found in S1 Data. Error bars represent binomial 95% confidence intervals calculated using JavaStat (http://statpages.info/confint.html). Chr, chromosome.