Comparison of biophysical and all-LIF simulations employing the IntFire1 or IntFire4 models.

(a) An example spike raster in response to a drifting grating in an all-LIF IntFire1 simulation. (b) Spontaneous rate, Rmax, OSI and DSI by cell type. (c) Spectra of multi-unit activity (weighted by 1/r, where r is the distance from the cell to the center of the system). This is used as a proxy to LFP, which cannot be directly computed for the point-neuron models. Note that exact match between this metric and the actual LFP computed for biophysical model (see Fig 3C) is not expected, but they both exhibit similar features, such as a prominent peak at ~20 Hz. (d) Distributions of lifetime sparsity of responses to gratings and movies, averaged over 10 trials. The data are for three directions of a grating (0, 45, and 90 degrees) and for three movies. (e) Distributions of LGN contribution to the total excitatory synaptic inputs across excitatory and inhibitory cells (in the IntFire1 and IntFire4 cases, this is computed for each cell as the average synaptic input over time and over all trials of the preferred orientation; see Methods), for TF = 2 Hz drifting gratings. (f) Distribution of OSI for excitatory cells for the LL, RL, LR, and RR cases.