Behavioral assessment in the open-field arena.

Crossing (A) and rearing (B) counts, and facial grooming time in seconds (C) of rats distributed into the different experimental groups, at 1, 2, 3, or 8 days after the dental surgical procedures. The box plots show the median of 5–8 experiments with the upper and lower quartiles. The whiskers indicate the maximal and the minimal values. (*P < .05; Kruskal-Wallis plus Dunn’s test).