Figure S8. (a) Correlation plot graphing T resp. proliferation suppression and myeloid IL-6 transcript suppression at 1:1 ratio of responding cells to MDSCs (R = .7288 p = 0.004). (b) IL-6 control experiment whereby MDSCs from controls (n = 6) and AD patients from various stages (n = 12) do not express IL-6 transcript when cultured alone in LPS/IFNγ treatments. Corroboration with no IL-6 protein in the MDSC only treated media when analyzed via ELISA (data not shown). (TIF 29 kb
Table S7. Changes in expression of AD-associated Blue, Magenta and Yellow microglial modules in agin...
Figure S6. Iba1+/TMEM119− cells represent a CD68+ macrophage population with peripheral origin highl...
No change in AD-related gene expression in LC neurons during disease progression. Bar graph shows ch...
Figure S6. (a) Correlation data between age and protein expression of HLADR and CD33 analyzed via fl...
Figure S5. (a) Correlation data between age and monocyte population changes. Analyses performed exam...
Figure S7. (a) Analysis of gender contribution to MDSC suppressive function on pro-inflammatory M1 c...
Results of multiple linear regression models without control for confounding variables. Values are β...
Results of multiple linear regression models with control for confounding variables. Values are β co...
Figure S2. Flow cytometry gating schemes for monocyte and MDSC populations. (TIF 539 kb
Figure S9. Nanostring dataset for RNA analysis of CDR rated patients and age-matched controls. (XLSX...
Table S1. Characteristics of the primary antibodies, immunohistochemistry conditions and expression ...
Table S6. Top AD risk genes in Blue, Magenta and Yellow AD-associated microglial modules. (XLSX 22Â ...
Table S1. Mouse microglial transcriptomic modules identified by Weighted Correlation Network Analysi...
Neutralization of CCL3 by a specific antibody. Astrocytes primed with 1 μg/ml LPS for 3 h were treat...
Figure S5. Modulation of the JAK2-STAT3 pathway does not change expression of proteins involved in A...
Table S7. Changes in expression of AD-associated Blue, Magenta and Yellow microglial modules in agin...
Figure S6. Iba1+/TMEM119− cells represent a CD68+ macrophage population with peripheral origin highl...
No change in AD-related gene expression in LC neurons during disease progression. Bar graph shows ch...
Figure S6. (a) Correlation data between age and protein expression of HLADR and CD33 analyzed via fl...
Figure S5. (a) Correlation data between age and monocyte population changes. Analyses performed exam...
Figure S7. (a) Analysis of gender contribution to MDSC suppressive function on pro-inflammatory M1 c...
Results of multiple linear regression models without control for confounding variables. Values are β...
Results of multiple linear regression models with control for confounding variables. Values are β co...
Figure S2. Flow cytometry gating schemes for monocyte and MDSC populations. (TIF 539 kb
Figure S9. Nanostring dataset for RNA analysis of CDR rated patients and age-matched controls. (XLSX...
Table S1. Characteristics of the primary antibodies, immunohistochemistry conditions and expression ...
Table S6. Top AD risk genes in Blue, Magenta and Yellow AD-associated microglial modules. (XLSX 22Â ...
Table S1. Mouse microglial transcriptomic modules identified by Weighted Correlation Network Analysi...
Neutralization of CCL3 by a specific antibody. Astrocytes primed with 1 μg/ml LPS for 3 h were treat...
Figure S5. Modulation of the JAK2-STAT3 pathway does not change expression of proteins involved in A...
Table S7. Changes in expression of AD-associated Blue, Magenta and Yellow microglial modules in agin...
Figure S6. Iba1+/TMEM119− cells represent a CD68+ macrophage population with peripheral origin highl...
No change in AD-related gene expression in LC neurons during disease progression. Bar graph shows ch...