Example of flow deficits analysis with the two scan protocols used in the study.

The two rows of images represent two optical coherence tomography angiography acquisitions (3X3 mm pattern in the top row and 6x6 mm patter in the bottom row) of the same subject. The angiogram of the superficial plexus (A and F) was used as a reference to center the grid in the center of the foveal avascular zone. The choriocapillaris (CC) angiogram (B and G) was automatically thresholded in order to obtain a binarized image (C and H) where the black pixels correspond to the CC flow deficits which were calculated superimposing the grid to the image. The percentage of flow deficits (FD%) was plotted versus the distance from the foveal center in order to obtain the resultant plots (E, J). The linear trendline (black line in E, J) of the curves were generated and the slopes and the intercepts of the corresponding equation were computed for further analysis.