This schematic shows the genetic organization of proviral HIV DNA and the HIV ‘transcription profiling’ assays targeting specific RNA sequence regions that provide insight into blocks to transcription. Some proposed mechanisms underlying the blocks to transcription initiation, elongation, and splicing are detailed.</p
We present a detailed and quantitative analysis of the functional characteristics of the 1,000-nucle...
The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of vi...
Transcription is a crucial step for human immunodeficiency virus type 1 (HIV-1) expression in all in...
<p>Panel A. Distribution of HIV reads along the vector genome. On the top is depicted the viral vect...
The retrovirus HIV-1 establishes lifelong infections, facilitated by integration, the covalent inser...
The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of vi...
We have investigated regulatory sequences in noncoding human DNA that are associated with repression...
The untranslated leader of the HIV-1 RNA genome contains some 350 nucleotides and is highly conserve...
During reverse transcription, the positive-strand HIV-1 RNA genome is converted into a double-strand...
HIV-1 provirus, either as a chromosomal integrant or as an episomal plasmid in HeLa cells, forms a t...
Transcription of the HIV-1 provirus produces a primary transcript that has terminally redundant poly...
Alternative splicing is critical to many cellular functions and appears to be primarily regulated th...
HIV-1-infected cells that persist despite antiretroviral therapy (ART) are frequently considered "tr...
We have used transient expression assays to study transcription directed by the human immunodeficien...
It has previously been shown that the human immunodeficiency virus type 1 (HIV-1) trans-activation-r...
We present a detailed and quantitative analysis of the functional characteristics of the 1,000-nucle...
The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of vi...
Transcription is a crucial step for human immunodeficiency virus type 1 (HIV-1) expression in all in...
<p>Panel A. Distribution of HIV reads along the vector genome. On the top is depicted the viral vect...
The retrovirus HIV-1 establishes lifelong infections, facilitated by integration, the covalent inser...
The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of vi...
We have investigated regulatory sequences in noncoding human DNA that are associated with repression...
The untranslated leader of the HIV-1 RNA genome contains some 350 nucleotides and is highly conserve...
During reverse transcription, the positive-strand HIV-1 RNA genome is converted into a double-strand...
HIV-1 provirus, either as a chromosomal integrant or as an episomal plasmid in HeLa cells, forms a t...
Transcription of the HIV-1 provirus produces a primary transcript that has terminally redundant poly...
Alternative splicing is critical to many cellular functions and appears to be primarily regulated th...
HIV-1-infected cells that persist despite antiretroviral therapy (ART) are frequently considered "tr...
We have used transient expression assays to study transcription directed by the human immunodeficien...
It has previously been shown that the human immunodeficiency virus type 1 (HIV-1) trans-activation-r...
We present a detailed and quantitative analysis of the functional characteristics of the 1,000-nucle...
The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of vi...
Transcription is a crucial step for human immunodeficiency virus type 1 (HIV-1) expression in all in...