(A and D) Immunofluorescence staining for LMOD1, Tomato and DAPI in the brachiocephalic artery of 24 week old Myh11-Cre-ERT2 ROSA26-STOP-tdTomato Apoe-/- mice fed high fat diet for 18 weeks. (B and C) LMOD1 and tomato expressing cells were identified in the fibrous cap (white arrows). (E and F) Another lesion showing LMOD1 and tomato expressing cells in the media (blue arrows). Tomato positive cells in the lesion stained negative for LMOD1 in the lesion. Images were captured using a 20x objective and are representative of n = 3 independent mice.</p
BACKGROUND: Mice deficient in the LDL receptor (Ldlr(-/-) mice) have been widely used as a model to ...
Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventiti...
<p>A) Serial frozen-thawed sections of the mouse abdominal aorta from wild type (i) or ApoE- deficie...
<p><b>A</b> therosclerosis-prone mice (males and females) lacking properdin were fed low fat or high...
<p><b>(A)</b> Consecutive sections of a left coronary artery (LCA) and a septal branch of the right ...
<p>Atherosclerotic lesions were induced in the carotid artery of LDLr<sup>−/−</sup> mice. The caroti...
<p><i>Tcf21</i><sup><i>lacZ/+</i></sup>, <i>ApoE</i><sup><i>-/-</i></sup> mice were fed HFD from 4 w...
<p>Analysis of atherosclerotic lesions was performed using the <i>en face</i> method. Representative...
<p><b>A</b>: Immunofluorescence of atherosclerotic lesions from 20 and 55 week-old ApoE KO mice. MØ ...
<p>Hearts were harvested from Paigen diet-fed apoE KO (A, C–D) and PDZK1/apoE dKO (B, E–F) mice as d...
<p>a) Representative images and quantitative analysis of atherosclerotic lesion size in the aortic s...
<p>Low-density lipoprotein receptor-knockout (LDLr KO) mice were fed a NFD (a), a HFD (b), a HFD wit...
Apo E3-leiden transgenic mice express human dysfunctional apo E variant and develop hyperlipidemia a...
<div><h3>Background</h3><p>Mice deficient in the LDL receptor (<em>Ldlr</em><sup>−/−</sup> mice) hav...
<p>Photograph of atherosclerotic lesion in the common carotid artery of apoE<sup>−/−</sup> mouse fed...
BACKGROUND: Mice deficient in the LDL receptor (Ldlr(-/-) mice) have been widely used as a model to ...
Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventiti...
<p>A) Serial frozen-thawed sections of the mouse abdominal aorta from wild type (i) or ApoE- deficie...
<p><b>A</b> therosclerosis-prone mice (males and females) lacking properdin were fed low fat or high...
<p><b>(A)</b> Consecutive sections of a left coronary artery (LCA) and a septal branch of the right ...
<p>Atherosclerotic lesions were induced in the carotid artery of LDLr<sup>−/−</sup> mice. The caroti...
<p><i>Tcf21</i><sup><i>lacZ/+</i></sup>, <i>ApoE</i><sup><i>-/-</i></sup> mice were fed HFD from 4 w...
<p>Analysis of atherosclerotic lesions was performed using the <i>en face</i> method. Representative...
<p><b>A</b>: Immunofluorescence of atherosclerotic lesions from 20 and 55 week-old ApoE KO mice. MØ ...
<p>Hearts were harvested from Paigen diet-fed apoE KO (A, C–D) and PDZK1/apoE dKO (B, E–F) mice as d...
<p>a) Representative images and quantitative analysis of atherosclerotic lesion size in the aortic s...
<p>Low-density lipoprotein receptor-knockout (LDLr KO) mice were fed a NFD (a), a HFD (b), a HFD wit...
Apo E3-leiden transgenic mice express human dysfunctional apo E variant and develop hyperlipidemia a...
<div><h3>Background</h3><p>Mice deficient in the LDL receptor (<em>Ldlr</em><sup>−/−</sup> mice) hav...
<p>Photograph of atherosclerotic lesion in the common carotid artery of apoE<sup>−/−</sup> mouse fed...
BACKGROUND: Mice deficient in the LDL receptor (Ldlr(-/-) mice) have been widely used as a model to ...
Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventiti...
<p>A) Serial frozen-thawed sections of the mouse abdominal aorta from wild type (i) or ApoE- deficie...