A) Trait evolution after an optimum shift and B) allele frequency dynamics during adaptation from a single replicate. The vertical line shows when the new trait optimum was reached and line colors denote effect sizes. Time is shown on a log scale. C) The phenotypic distribution and D) site frequency spectra of segregating mutations (black) and neutral expectation (red) from 100 independent replicates. Panels show different generations including equilibrium prior to adaptation (0), during adaptation (0.005), just before the new optimum is reached (0.01), after the new optimum has been reached (0.02), and the final generation (0.1). All results are from a simulated population with constant population size, σm = 0.05, and VS = 1.</p
When selection is acting on a large genetically diverse population, beneficial alleles increase in f...
<p>(<b>a</b>) Trait (in blue) closely matches the environmental gradient (grey) along the x-axis. (<...
<p>Example of a single simulation run. Panel A) shows the evolution of the population mean level of ...
The genetic architecture of adaptation in natural populations has not yet been resolved: it is not c...
<p>Panels in the upper row show averaged allele frequency dynamics over 25 generations after an alle...
<p>For all five parameter combinations, we use <i>c</i> = 10<sup>−11</sup>. Most simulations reach e...
A) The evolution of trait value and B) genetic variance during adaptation to a new trait optimum for...
Evolutionary theory has produced two conflicting paradigms for the adaptation of a polygenic trait. ...
(A-C) Observed frequency of region-wide haplotypes (RWH) during experimental evolution, for region 1...
A) Time to reach new trait optimum B) Rate of change in phenotype C) Genetic variance after 0.1 × Na...
Understanding the genetic basis of phenotypic adaptation to changing environments is an essential go...
<div> <div> <div> <p>Understanding the genetic basis of phenotypic adaptation to changing environmen...
<p>The number of origins of adaptive mutations on unique haplotype backgrounds was measured in simul...
When selection is acting on a large genetically diverse population, beneficial alleles increase in f...
<p>These diagrams indicate the proportion of alleles through time, with each color series representi...
When selection is acting on a large genetically diverse population, beneficial alleles increase in f...
<p>(<b>a</b>) Trait (in blue) closely matches the environmental gradient (grey) along the x-axis. (<...
<p>Example of a single simulation run. Panel A) shows the evolution of the population mean level of ...
The genetic architecture of adaptation in natural populations has not yet been resolved: it is not c...
<p>Panels in the upper row show averaged allele frequency dynamics over 25 generations after an alle...
<p>For all five parameter combinations, we use <i>c</i> = 10<sup>−11</sup>. Most simulations reach e...
A) The evolution of trait value and B) genetic variance during adaptation to a new trait optimum for...
Evolutionary theory has produced two conflicting paradigms for the adaptation of a polygenic trait. ...
(A-C) Observed frequency of region-wide haplotypes (RWH) during experimental evolution, for region 1...
A) Time to reach new trait optimum B) Rate of change in phenotype C) Genetic variance after 0.1 × Na...
Understanding the genetic basis of phenotypic adaptation to changing environments is an essential go...
<div> <div> <div> <p>Understanding the genetic basis of phenotypic adaptation to changing environmen...
<p>The number of origins of adaptive mutations on unique haplotype backgrounds was measured in simul...
When selection is acting on a large genetically diverse population, beneficial alleles increase in f...
<p>These diagrams indicate the proportion of alleles through time, with each color series representi...
When selection is acting on a large genetically diverse population, beneficial alleles increase in f...
<p>(<b>a</b>) Trait (in blue) closely matches the environmental gradient (grey) along the x-axis. (<...
<p>Example of a single simulation run. Panel A) shows the evolution of the population mean level of ...