High grade tumors have strong staining for Rb S249 phosphorylation.
- Jaileene Pérez-Morales (5988131)
- Darielys Mejías-Morales (5988134)
- Stephanie Rivera-Rivera (5988137)
- Jonathan González-Flores (5988140)
- Mónica González-Loperena (5988143)
- Fernando Y. Cordero-Báez (5988146)
- Wilfredo M. Pedreira-García (5988149)
- Camille Chardón-Colón (5988152)
- Jennifer Cabán-Rivera (5988155)
- W. Douglas Cress (198903)
- Edna R. Gordian (5988158)
- Teresita Muñoz-Antonia (591147)
- Mauricio Cabrera-Ríos (5988161)
- Angel Isidro (5988164)
- Domenico Coppola (53952)
- Marilin Rosa (5988167)
- Theresa A. Boyle (5988170)
- Victoria Izumi (5988173)
- John M. Koomen (228649)
- Pedro G. Santiago-Cardona (237764)
Publication date
November 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
IHC staining showing a strong nuclear staining for phospho-Rb S249 in four high grade SCC tissue cores (A). These four SCC cores all had a tumor grading of 3 and a Rb phospho-S249 staining score of 3. In contrast, grade 1 SCC cores had a Rb phospho-S249 staining score of 0 (B). Panels at the bottom of each figure are negative controls in which the primary antibody was omitted from the IHC protocol.</p
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