Figure S4. Cytokine and MMP expression in human breast cancer patients. Analysis of gene expression from the METABRIC dataset. (A-C) Boxplot representation of IL-6 (A) (Student’s t test, P 1) IGF-1R expression (Student’s t test, MMP2, P < 6.864 × 10− 10; CHOP, P < 3.172 × 10− 10). (TIF 253 kb
Figure S7. Assessment of dynamic changes in expression of cell cycle regulatory genes. (a) Log2 diff...
Figure S3. Volcano plot displays the fold change (FC) and statistical significance (FDR) values of g...
Figure S1. Gene expression in breast cancer. a Volcano plot of gene expression changes in the transc...
Figure S2. IL-6 protein expression is increased in tumor cells with reduced IGF signaling. ELISA ana...
Figure S5. Wnt2 and Frizzled9 expression are inversely correlated with IGF-1R expression in breast c...
Table S3. Cytokine and chemokine profile is altered in MMTV-Wnt1 tumors with attenuated IGF-1R. Gene...
Figure S3. Reduced IGF-1R in primary tumors does not alter the active T cell population. (A, B) Quan...
Table S1. MMTV-Wnt1 tumor phenotype is altered with reduced IGF-1R [1]. (DOCX 16 kb
Figure S1. IMC-A12 blocks activation of IGF-1R signaling. Western blot analysis of pAkt (473) and pI...
OSI-906 inhibits p-IGF1R and IGF1R signaling factors in breast cancer cell-lines. 3 × 105 ER-positiv...
Immunohistochemistry and manual scoring analysis of Australian Breast Cancer Tissue Bank patient sam...
Western blot immunoassay for the detection of nuclear receptors in MCF7 and BT-474 breast cancer cel...
Prognostic survival outcomes in relation to IGF1R protein expression in HER2 and PR-positive and neg...
Figure S1. Representative photos of TG2-overexpressing MCF7 cells (MCF7_TG2) and control vector-tran...
Immunohistochemical analysis of nuclear IGFBP-3 in HCC1806 tumors from control, gefitinib-treated (G...
Figure S7. Assessment of dynamic changes in expression of cell cycle regulatory genes. (a) Log2 diff...
Figure S3. Volcano plot displays the fold change (FC) and statistical significance (FDR) values of g...
Figure S1. Gene expression in breast cancer. a Volcano plot of gene expression changes in the transc...
Figure S2. IL-6 protein expression is increased in tumor cells with reduced IGF signaling. ELISA ana...
Figure S5. Wnt2 and Frizzled9 expression are inversely correlated with IGF-1R expression in breast c...
Table S3. Cytokine and chemokine profile is altered in MMTV-Wnt1 tumors with attenuated IGF-1R. Gene...
Figure S3. Reduced IGF-1R in primary tumors does not alter the active T cell population. (A, B) Quan...
Table S1. MMTV-Wnt1 tumor phenotype is altered with reduced IGF-1R [1]. (DOCX 16 kb
Figure S1. IMC-A12 blocks activation of IGF-1R signaling. Western blot analysis of pAkt (473) and pI...
OSI-906 inhibits p-IGF1R and IGF1R signaling factors in breast cancer cell-lines. 3 × 105 ER-positiv...
Immunohistochemistry and manual scoring analysis of Australian Breast Cancer Tissue Bank patient sam...
Western blot immunoassay for the detection of nuclear receptors in MCF7 and BT-474 breast cancer cel...
Prognostic survival outcomes in relation to IGF1R protein expression in HER2 and PR-positive and neg...
Figure S1. Representative photos of TG2-overexpressing MCF7 cells (MCF7_TG2) and control vector-tran...
Immunohistochemical analysis of nuclear IGFBP-3 in HCC1806 tumors from control, gefitinib-treated (G...
Figure S7. Assessment of dynamic changes in expression of cell cycle regulatory genes. (a) Log2 diff...
Figure S3. Volcano plot displays the fold change (FC) and statistical significance (FDR) values of g...
Figure S1. Gene expression in breast cancer. a Volcano plot of gene expression changes in the transc...