Additional file 3: of Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion
- Sara Rhost (240730)
- Éamon Hughes (5990417)
- Hannah Harrison (206704)
- Svanheidur Rafnsdottir (5990420)
- Hanna Jacobsson (5990423)
- Pernilla Gregersson (5990426)
- Ylva Magnusson (159239)
- Paul Fitzpatrick (3689143)
- Daniel Andersson (437409)
- Karoline Berger (5990429)
- Anders Ståhlberg (51867)
- Göran Landberg (90307)
Publication date
November 2018
DOIAbstract
The small orally available sortilin inhibitor AF38469 do not impact cell viability. Relative proliferation of MCF7 and MDA-MB 231 cells 48 h after treatment with vehicle (PBS/DMSO), AF38469 (3 μg/ml), progranulin (PGRN) (1 μg/ml) or AF38469 (3 μg/ml) and PGRN (1 μg/ml) by Alamar Blue assay. (TIFF 134 kb
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