Figure S2. Immunoblotting data of main Fig. 2c, d and f were quantified using Image J software and shown in Additional file 2: Figure S2A, 2B and 2C, respectively. Data were the mean ± S.E.M. from 3 independent experiments. *p < 0.05, indicating the significant effects of BzATP and nigericin; #p < 0.05, indicating the antagonist effects of mitoTEMPO and STO-609 on the action of BzATP and nigericin. (TIF 2618 kb
Figure S2. Efficient and selective inactivation of MFP2 in microglia in Cx3cr1-Mfp2−/− mice. (A) Mic...
Figure S2. Simultaneous stimulation of primary microglia with LPS plus IL4. * p < 0.05, ** p < 0.01,...
A-769662 activated AMPK downstream targets involved in regulation of mitochondrial function. BMDMs w...
Figure S1. Immunoblotting data of main Fig. 1a-c were quantified using Image J software. Data were t...
Figure S3. Immunoblotting analysis of main Fig. 3 were quantified using Image J software. Data were ...
Concentration and time-dependent responses of microglia in IL1β release upon LPS plus BzATP stimulat...
Figure S3. P2X7Rs do not regulate microglial intracellular pH, IL-1β/IL-18 release, blebbing, or pho...
Cultured human microglia do not bleb in response to ATP. Microglia cultured on chamber slides were e...
Figure S4. P2X7R dye uptake is independent of cell lysis and selective for cations below a certain t...
Figure S2. Microglia P2X7Rs are dynamically regulated by bacterial phagocytosis. (a) The current-vol...
PKD family inhibition abrogates LPA-mediated downstream signaling. (A) BV-2 microglia cells were cul...
Related to Fig. 2 (a) Representative immunoblots of total lysates of BV2 cells treated with 100 μM M...
LPAR5 controls LPA-mediated downstream signaling. (A) BV-2 microglia cells were cultured in 6-well p...
The details of primary mouse microglial cell culture. Figure S1. Iba-1 immunostaining images and mor...
BV2 microglia in co-culture system exacerbated neuronal loss under AβO exposure. HT-22 cells were tr...
Figure S2. Efficient and selective inactivation of MFP2 in microglia in Cx3cr1-Mfp2−/− mice. (A) Mic...
Figure S2. Simultaneous stimulation of primary microglia with LPS plus IL4. * p < 0.05, ** p < 0.01,...
A-769662 activated AMPK downstream targets involved in regulation of mitochondrial function. BMDMs w...
Figure S1. Immunoblotting data of main Fig. 1a-c were quantified using Image J software. Data were t...
Figure S3. Immunoblotting analysis of main Fig. 3 were quantified using Image J software. Data were ...
Concentration and time-dependent responses of microglia in IL1β release upon LPS plus BzATP stimulat...
Figure S3. P2X7Rs do not regulate microglial intracellular pH, IL-1β/IL-18 release, blebbing, or pho...
Cultured human microglia do not bleb in response to ATP. Microglia cultured on chamber slides were e...
Figure S4. P2X7R dye uptake is independent of cell lysis and selective for cations below a certain t...
Figure S2. Microglia P2X7Rs are dynamically regulated by bacterial phagocytosis. (a) The current-vol...
PKD family inhibition abrogates LPA-mediated downstream signaling. (A) BV-2 microglia cells were cul...
Related to Fig. 2 (a) Representative immunoblots of total lysates of BV2 cells treated with 100 μM M...
LPAR5 controls LPA-mediated downstream signaling. (A) BV-2 microglia cells were cultured in 6-well p...
The details of primary mouse microglial cell culture. Figure S1. Iba-1 immunostaining images and mor...
BV2 microglia in co-culture system exacerbated neuronal loss under AβO exposure. HT-22 cells were tr...
Figure S2. Efficient and selective inactivation of MFP2 in microglia in Cx3cr1-Mfp2−/− mice. (A) Mic...
Figure S2. Simultaneous stimulation of primary microglia with LPS plus IL4. * p < 0.05, ** p < 0.01,...
A-769662 activated AMPK downstream targets involved in regulation of mitochondrial function. BMDMs w...