Publication date
November 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
Visual comparisons on nine of the target proteins (the native and predicted structures are in red and green, respectively).</p
Visual comparisons on nine of the target proteins (the native and predicted structures are in red and green, respectively).</p
<p>White bars represent the predicted relevant target space, whereas the different prioritized subse...
<p>Predicted structures of ERRa and ERRb proteins superimposed between wt and G insertion. (A) Super...
<p>Critical amino acids for antibody binding are indicated in the modelling structure as the sites t...
The highlighted structures from left to right are the native, the structures of the best Cα-RMSD, an...
<p>The protein is shown in blue, the native RNA in red and the RNA candidates in yellow. For each pd...
<p>Native structure and DNA are represented by green and orange, respectively. The predicted structu...
<p>Alpha helixes are in red, beta sheets are in yellow, turns are in green. A diverse set of protein...
<p>Alpha helixes are in red, beta sheets are in yellow, turns are in green. A diverse set of protein...
<p>Overlap of the scatterplots for the two classes of proteins for each variable pairs. Random prote...
<p>Superimposition and structural comparison of three proteins: <i>Ab</i>PncA (blue), <i>Sp</i>Nic (...
<p>Left: Rps0a for the AP group. Right: Cpr1 of the NAP group. The secondary structures of the prote...
<p>Examples of how target protein structure can assist drug discovery and development.</p
<p>Panels (A) to (D) demonstrate four proteins with two-class prediction MCC of 0.650, 0.454, 0.262,...
<p>(A) A cartoon depiction of cluster of adjacent residues is shown (red circle). (B) Structural ali...
<p>Known down-regulated proteins are represented as hexagons. Known up-regulated proteins are repres...
<p>White bars represent the predicted relevant target space, whereas the different prioritized subse...
<p>Predicted structures of ERRa and ERRb proteins superimposed between wt and G insertion. (A) Super...
<p>Critical amino acids for antibody binding are indicated in the modelling structure as the sites t...
The highlighted structures from left to right are the native, the structures of the best Cα-RMSD, an...
<p>The protein is shown in blue, the native RNA in red and the RNA candidates in yellow. For each pd...
<p>Native structure and DNA are represented by green and orange, respectively. The predicted structu...
<p>Alpha helixes are in red, beta sheets are in yellow, turns are in green. A diverse set of protein...
<p>Alpha helixes are in red, beta sheets are in yellow, turns are in green. A diverse set of protein...
<p>Overlap of the scatterplots for the two classes of proteins for each variable pairs. Random prote...
<p>Superimposition and structural comparison of three proteins: <i>Ab</i>PncA (blue), <i>Sp</i>Nic (...
<p>Left: Rps0a for the AP group. Right: Cpr1 of the NAP group. The secondary structures of the prote...
<p>Examples of how target protein structure can assist drug discovery and development.</p
<p>Panels (A) to (D) demonstrate four proteins with two-class prediction MCC of 0.650, 0.454, 0.262,...
<p>(A) A cartoon depiction of cluster of adjacent residues is shown (red circle). (B) Structural ali...
<p>Known down-regulated proteins are represented as hexagons. Known up-regulated proteins are repres...
<p>White bars represent the predicted relevant target space, whereas the different prioritized subse...
<p>Predicted structures of ERRa and ERRb proteins superimposed between wt and G insertion. (A) Super...
<p>Critical amino acids for antibody binding are indicated in the modelling structure as the sites t...
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