Additional file 2: of Recombination-independent rapid convergent evolution of the gastric pathogen Helicobacter pylori

Figure S1. Frequency of recombinant regions as detected by PhiPack using single (intra-genic) vs. multiple (inter-genic) genes in ‘global’ subset and ‘local’ (Amerindian) subset of strains (as denoted in Fig. 1). Figure S2. The synDss statistic landscapes for 50 randomly selected core genes of H. pylori: (A) 25 recombinant and (B) 25 non-recombinant, as designated by three recombination detection statistics in PhiPack software. Figure S3. Average frequency distribution of mutations in encoded proteins of randomly selected subsets of H. pylori non-recombinant core genes with convergent mutations. Figure S4. Average frequency distribution of mutations of encoded proteins in simulated datasets of 25 H. pylori genes (one of the randomly selected replicates from Figure S3) using two different mutation-rate constraints. (PDF 2545 kb