Figure S1. Ivermectin potentiates P2X7R current. ATP was applied every 15 s in the absence and presence of 20 μM ivermectin. (a) 100 μM ATP (green bars) failed to evoke significant membrane current even in the presence of ivermectin (orange bar). In contrast, 10 mM ATP (light blue bars) evoked robust inward currents. (b) The current evoked by 10 mM ATP is potentiated by co-application of 20 μM ivermectin. (EPS 5969 kb
Figure S2. Primary microglia viability was detected by MTS assay. Primary microglia was treated with...
Contains fulltext : 89873.pdf (publisher's version ) (Closed access)Extracellular ...
Figure S2. Immunoblotting data of main Fig. 2c, d and f were quantified using Image J software and s...
Figure S2. Microglia P2X7Rs are dynamically regulated by bacterial phagocytosis. (a) The current-vol...
Figure S4. P2X7R dye uptake is independent of cell lysis and selective for cations below a certain t...
Figure S3. P2X7Rs do not regulate microglial intracellular pH, IL-1β/IL-18 release, blebbing, or pho...
Cultured human microglia do not bleb in response to ATP. Microglia cultured on chamber slides were e...
Figure S1. Immunoblotting data of main Fig. 1a-c were quantified using Image J software. Data were t...
Concentration and time-dependent responses of microglia in IL1β release upon LPS plus BzATP stimulat...
Figure S3. Immunoblotting analysis of main Fig. 3 were quantified using Image J software. Data were ...
Figure S1. ATP-induced microglial migration using the transwell assay. B6M7, BV2 cells and peritonea...
2 The opening of pannexin-1 (Px1) hemichannels is regulated by the activity of P2X7 receptors (P2X7R...
Figure S1. A) Von Frey filament, and grip strength analysis for BupOH and TTX at days 1 and 5. B) Vo...
Abstract Background The ATP-gated ionotropic P2X7 receptor (P2X7R) has the unusual ability to functi...
Figure S2. A) Proliferation analysis of different purinergic agonists in the presence of a P2y1 anta...
Figure S2. Primary microglia viability was detected by MTS assay. Primary microglia was treated with...
Contains fulltext : 89873.pdf (publisher's version ) (Closed access)Extracellular ...
Figure S2. Immunoblotting data of main Fig. 2c, d and f were quantified using Image J software and s...
Figure S2. Microglia P2X7Rs are dynamically regulated by bacterial phagocytosis. (a) The current-vol...
Figure S4. P2X7R dye uptake is independent of cell lysis and selective for cations below a certain t...
Figure S3. P2X7Rs do not regulate microglial intracellular pH, IL-1β/IL-18 release, blebbing, or pho...
Cultured human microglia do not bleb in response to ATP. Microglia cultured on chamber slides were e...
Figure S1. Immunoblotting data of main Fig. 1a-c were quantified using Image J software. Data were t...
Concentration and time-dependent responses of microglia in IL1β release upon LPS plus BzATP stimulat...
Figure S3. Immunoblotting analysis of main Fig. 3 were quantified using Image J software. Data were ...
Figure S1. ATP-induced microglial migration using the transwell assay. B6M7, BV2 cells and peritonea...
2 The opening of pannexin-1 (Px1) hemichannels is regulated by the activity of P2X7 receptors (P2X7R...
Figure S1. A) Von Frey filament, and grip strength analysis for BupOH and TTX at days 1 and 5. B) Vo...
Abstract Background The ATP-gated ionotropic P2X7 receptor (P2X7R) has the unusual ability to functi...
Figure S2. A) Proliferation analysis of different purinergic agonists in the presence of a P2y1 anta...
Figure S2. Primary microglia viability was detected by MTS assay. Primary microglia was treated with...
Contains fulltext : 89873.pdf (publisher's version ) (Closed access)Extracellular ...
Figure S2. Immunoblotting data of main Fig. 2c, d and f were quantified using Image J software and s...