Additional file 1: of Anti-inflammatory and anti-oxidant mechanisms of an MMP-8 inhibitor in lipoteichoic acid-stimulated rat primary astrocytes: involvement of NF-ÎşB, Nrf2, and PPAR-Îł signaling pathways | ORKG Ask

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Additional file 1: of Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration

Satoshi Suzuki (113746)
Nobuyuki Fujita (184762)
Naobumi Hosogane (552063)
Kota Watanabe (453664)
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is Figure S1 showing molecular phenotype of the passaged rat AF cells. Real-time RT-PCR analysis of ...

Additional file 8: of Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

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Lucile Ben Haim (5857157)
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Océane Guillemaud (5857169)
Marie-Ange Palomares (5066984)
Laurene Abjean (5857172)
Fanny Petit (305899)
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Marie-Claude Gaillard (46536)
Martine Guillermier (105289)
Sueva Bernier (5857178)
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Gwenaëlle Aurégan (5857184)
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Nathalie Déchamps (5857190)
Julien Veran (5857193)
Valentin Langlais (5857196)
Karine Cambon (374264)
Alexis Bemelmans (5857199)
Jan Baijer (118248)
Gilles Bonvento (368370)
Marc Dhenain (305906)
Jean-François Deleuze (3626111)
Stéphane Oliet (5857202)
Emmanuel Brouillet (46542)
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Table S3. Expression of phagocytic receptors and genes in astrocytes RNAseq analysis of astrocytes s...

Additional file 1: of Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells

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Albrecht Keil (5990435)
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Expression of GPR55 mRNA in primary rat microglia with or without LPS stimulation. Microglia were in...

Additional file 2: of Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration

Satoshi Suzuki (113746)
Nobuyuki Fujita (184762)
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Yoshiaki Toyama (12534)
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is Figure S2 showing treatment of MAPK inhibitors to AF cells with ROS. Real-time RT-PCR analysis of...

Additional file 2: Figure S2. of αVβ3 Integrin regulates astrocyte reactivity

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Representative western blot of β3 Integrin from rat astrocytes treated with Il-6, IL+db cAMP, IL-1β,...

Additional file 1: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

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Marcus Rust (5799692)
Sarah Kaiser (5799695)
Alexander Slowik (5799698)
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Figure S2. Cell counting revealed 95.2% astrocytes and 4.5% microglia. Approximately 0.4% of the cel...

Additional file 1: of Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes

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Rosa Di Liddo (1622587)
Laura Facci (3410714)
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Figure S1–S4. Figure S1 l-leucyl-l-leucine methyl ester (L-LME) depletes enriched astrocytes of micr...

Additional file 1: of The small molecule CA140 inhibits the neuroinflammatory response in wild-type mice and a mouse model of AD

Ju-Young Lee (5771681)
Jin Nam (206241)
Youngpyo Nam (5771684)
Hye Nam (5771675)
Gwangho Yoon (5771678)
Eunhwa Ko (531562)
Sang-Bum Kim (3058971)
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Takaoki Koyanagi (4262767)
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Figure S1. Post-treatment with CA140 at 5 μM only significantly reduced LPS-induced IL-1β mRNA level...

Additional file 2: of Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells

Soraya Saliba (3706465)
Hannah Jauch (5990432)
Brahim Gargouri (5279828)
Albrecht Keil (5990435)
Thomas Hurrle (5990438)
Nicole Volz (1947688)
Florian Mohr (5990441)
Mario van der Stelt (222751)
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November 2018

First screening of chemical-related synthesized compounds (KIT 1 - KIT 21) on LPS-induced PGE2 synth...

Additional file 2: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

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Sarah Kaiser (5799695)
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Andreas Koczulla (3555509)
Jörg Schulz (4018502)
Pardes Habib (5799701)
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September 2018

Figure S1. There are no oligodendrocytes contaminating the cell culture. Non-specific binding of Oli...

Additional file 5: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

Taraneh Ebrahimi (5799689)
Marcus Rust (5799692)
Sarah Kaiser (5799695)
Alexander Slowik (5799698)
Cordian Beyer (2733838)
Andreas Koczulla (3555509)
Jörg Schulz (4018502)
Pardes Habib (5799701)
Jan Bach (5799704)

November 2018

Figure S5. (A) Since there are no oligodendrocytes contaminating the cell culture, NLRP3-expression ...

Additional file 1: Figure S1. of Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation

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Tom Seijkens (1651360)
Pascal Kusters (4021484)
Susanne van der Pol (3448436)
Barbara Zarzycka (1651357)
Priscilla Heijnen (4021496)
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Immune cell accumulation in the spinal cords of EAE rats is reduced by SMI 6877002 treatment. Gene e...

Additional file 1: of Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures

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TG2 and fibronectin protein expression in rat astrocytes and microglia. Untreated (Ctrl) and 48 h LP...

Additional file 1: of Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

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Zemin Di (6332741)
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Yuxian Shen (454391)

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Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...

Additional file 1: of Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration

Satoshi Suzuki (113746)
Nobuyuki Fujita (184762)
Naobumi Hosogane (552063)
Kota Watanabe (453664)
Ken Ishii (216041)
Yoshiaki Toyama (12534)
Keiyo Takubo (115554)
Keisuke Horiuchi (239396)
Takeshi Miyamoto (163168)
Masaya Nakamura (121832)
Morio Matsumoto (289101)

November 2015

is Figure S1 showing molecular phenotype of the passaged rat AF cells. Real-time RT-PCR analysis of ...

Additional file 8: of Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

Kelly Ceyzériat (5857151)
Lucile Ben Haim (5857157)
Audrey Denizot (5857160)
Dylan Pommier (5857166)
Marco Matos (3504314)
Océane Guillemaud (5857169)
Marie-Ange Palomares (5066984)
Laurene Abjean (5857172)
Fanny Petit (305899)
Pauline Gipchtein (5857175)
Marie-Claude Gaillard (46536)
Martine Guillermier (105289)
Sueva Bernier (5857178)
Mylène Gaudin (5857181)
Gwenaëlle Aurégan (5857184)
Charlène Joséphine (5857187)
Nathalie Déchamps (5857190)
Julien Veran (5857193)
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Karine Cambon (374264)
Alexis Bemelmans (5857199)
Jan Baijer (118248)
Gilles Bonvento (368370)
Marc Dhenain (305906)
Jean-François Deleuze (3626111)
Stéphane Oliet (5857202)
Emmanuel Brouillet (46542)
Philippe Hantraye (46540)
Maria-Angeles Carrillo-de Sauvage (5857205)
Robert Olaso (82489)
Aude Panatier (74725)
Carole Escartin (368366)

October 2018

Table S3. Expression of phagocytic receptors and genes in astrocytes RNAseq analysis of astrocytes s...

Additional file 1: of Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells

Soraya Saliba (3706465)
Hannah Jauch (5990432)
Brahim Gargouri (5279828)
Albrecht Keil (5990435)
Thomas Hurrle (5990438)
Nicole Volz (1947688)
Florian Mohr (5990441)
Mario van der Stelt (222751)
Stefan Bräse (2454700)
Bernd Fiebich (781952)

November 2018

Expression of GPR55 mRNA in primary rat microglia with or without LPS stimulation. Microglia were in...

Additional file 2: of Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration

Satoshi Suzuki (113746)
Nobuyuki Fujita (184762)
Naobumi Hosogane (552063)
Kota Watanabe (453664)
Ken Ishii (216041)
Yoshiaki Toyama (12534)
Keiyo Takubo (115554)
Keisuke Horiuchi (239396)
Takeshi Miyamoto (163168)
Masaya Nakamura (121832)
Morio Matsumoto (289101)

November 2015

is Figure S2 showing treatment of MAPK inhibitors to AF cells with ROS. Real-time RT-PCR analysis of...

Additional file 2: Figure S2. of αVβ3 Integrin regulates astrocyte reactivity

Raúl Lagos-Cabré (669869)
Alvaro Alvarez (3538508)
Milene Kong (4480396)
Francesca Burgos-Bravo (4480393)
Areli Cárdenas (4480387)
Edgardo Rojas-Mancilla (4480384)
Ramón Pérez-Nuñez (4480390)
Rodrigo Herrera-Molina (174513)
Fabiola Rojas (4480399)
Pascal Schneider (46636)
Mario Herrera-Marschitz (19968)
Andrew Quest (4480402)
Brigitte van Zundert (547715)
Lisette Leyton (172553)

September 2017

Representative western blot of β3 Integrin from rat astrocytes treated with Il-6, IL+db cAMP, IL-1β,...

Additional file 1: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

Taraneh Ebrahimi (5799689)
Marcus Rust (5799692)
Sarah Kaiser (5799695)
Alexander Slowik (5799698)
Cordian Beyer (2733838)
Andreas Koczulla (3555509)
Jörg Schulz (4018502)
Pardes Habib (5799701)
Jan Bach (5799704)

September 2018

Figure S2. Cell counting revealed 95.2% astrocytes and 4.5% microglia. Approximately 0.4% of the cel...

Additional file 1: of Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes

Carla Marinelli (3410711)
Rosa Di Liddo (1622587)
Laura Facci (3410714)
Thomas Bertalot (3410717)
Maria Conconi (3410720)
Morena Zusso (3410705)
Stephen Skaper (3410723)
Pietro Giusti (3410708)

December 2015

Figure S1–S4. Figure S1 l-leucyl-l-leucine methyl ester (L-LME) depletes enriched astrocytes of micr...

Additional file 1: of The small molecule CA140 inhibits the neuroinflammatory response in wild-type mice and a mouse model of AD

Ju-Young Lee (5771681)
Jin Nam (206241)
Youngpyo Nam (5771684)
Hye Nam (5771675)
Gwangho Yoon (5771678)
Eunhwa Ko (531562)
Sang-Bum Kim (3058971)
Mahealani Bautista (5849960)
Christina Capule (5849963)
Takaoki Koyanagi (4262767)
Geoffray Leriche (1428952)
Hwan Geun Choi (750017)
Jerry Yang (127786)
Jeongyeon Kim (344029)
Hyang-Sook Hoe (230145)

November 2018

Figure S1. Post-treatment with CA140 at 5 μM only significantly reduced LPS-induced IL-1β mRNA level...

Additional file 2: of Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells

Soraya Saliba (3706465)
Hannah Jauch (5990432)
Brahim Gargouri (5279828)
Albrecht Keil (5990435)
Thomas Hurrle (5990438)
Nicole Volz (1947688)
Florian Mohr (5990441)
Mario van der Stelt (222751)
Stefan BrĂ¤se (4468327)
Bernd Fiebich (781952)

November 2018

First screening of chemical-related synthesized compounds (KIT 1 - KIT 21) on LPS-induced PGE2 synth...

Additional file 2: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

Taraneh Ebrahimi (5799689)
Marcus Rust (5799692)
Sarah Kaiser (5799695)
Alexander Slowik (5799698)
Cordian Beyer (2733838)
Andreas Koczulla (3555509)
Jörg Schulz (4018502)
Pardes Habib (5799701)
Jan Bach (5799704)

September 2018

Figure S1. There are no oligodendrocytes contaminating the cell culture. Non-specific binding of Oli...

Additional file 5: of α1-antitrypsin mitigates NLRP3-inflammasome activation in amyloid β1–42-stimulated murine astrocytes

Taraneh Ebrahimi (5799689)
Marcus Rust (5799692)
Sarah Kaiser (5799695)
Alexander Slowik (5799698)
Cordian Beyer (2733838)
Andreas Koczulla (3555509)
Jörg Schulz (4018502)
Pardes Habib (5799701)
Jan Bach (5799704)

November 2018

Figure S5. (A) Since there are no oligodendrocytes contaminating the cell culture, NLRP3-expression ...

Additional file 1: Figure S1. of Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation

Suzanne Aarts (4021490)
Tom Seijkens (1651360)
Pascal Kusters (4021484)
Susanne van der Pol (3448436)
Barbara Zarzycka (1651357)
Priscilla Heijnen (4021496)
Linda Beckers (599653)
Myrthe den Toom (3193347)
Marion Gijbels (4021487)
Louis Boon (87167)
Christian Weber (86566)
Helga de Vries (3448448)
Gerry Nicolaes (4021481)
Christine Dijkstra (4021493)
Gijs Kooij (256414)
Esther Lutgens (358987)

May 2017

Immune cell accumulation in the spinal cords of EAE rats is reduced by SMI 6877002 treatment. Gene e...

Additional file 1: of Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures

Nathaly Espitia Pinzón (4722132)
John Brevé (4710978)
John Bol (4722126)
Benjamin Drukarch (204897)
Wia Baron (594608)
Anne-Marie van Dam (204899)

December 2017

TG2 and fibronectin protein expression in rat astrocytes and microglia. Untreated (Ctrl) and 48 h LP...

Additional file 1: of Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress

Shengchun Xu (5060504)
Zemin Di (6332741)
Yufeng He (5673119)
Runjie Wang (6332744)
Yuyang Ma (3695131)
Rui Sun (177521)
Jing Li (10611)
Tao Wang (12008)
Yujun Shen (3412115)
Shengyun Fang (207485)
Lijie Feng (3412118)
Yuxian Shen (454391)

February 2019

Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...

Additional file 1: of Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration

Satoshi Suzuki (113746)
Nobuyuki Fujita (184762)
Naobumi Hosogane (552063)
Kota Watanabe (453664)
Ken Ishii (216041)
Yoshiaki Toyama (12534)
Keiyo Takubo (115554)
Keisuke Horiuchi (239396)
Takeshi Miyamoto (163168)
Masaya Nakamura (121832)
Morio Matsumoto (289101)

November 2015

is Figure S1 showing molecular phenotype of the passaged rat AF cells. Real-time RT-PCR analysis of ...

Additional file 8: of Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

Kelly Ceyzériat (5857151)
Lucile Ben Haim (5857157)
Audrey Denizot (5857160)
Dylan Pommier (5857166)
Marco Matos (3504314)
Océane Guillemaud (5857169)
Marie-Ange Palomares (5066984)
Laurene Abjean (5857172)
Fanny Petit (305899)
Pauline Gipchtein (5857175)
Marie-Claude Gaillard (46536)
Martine Guillermier (105289)
Sueva Bernier (5857178)
Mylène Gaudin (5857181)
Gwenaëlle Aurégan (5857184)
Charlène Joséphine (5857187)
Nathalie Déchamps (5857190)
Julien Veran (5857193)
Valentin Langlais (5857196)
Karine Cambon (374264)
Alexis Bemelmans (5857199)
Jan Baijer (118248)
Gilles Bonvento (368370)
Marc Dhenain (305906)
Jean-François Deleuze (3626111)
Stéphane Oliet (5857202)
Emmanuel Brouillet (46542)
Philippe Hantraye (46540)
Maria-Angeles Carrillo-de Sauvage (5857205)
Robert Olaso (82489)
Aude Panatier (74725)
Carole Escartin (368366)

October 2018

Table S3. Expression of phagocytic receptors and genes in astrocytes RNAseq analysis of astrocytes s...