Additional file 5. All relevant methylated sites of the five methylation-driven genes obtained from the TCGA database. (1–16) methylated sites of the gene CCDC181; (17–33) methylated sites of the gene ELF3; (34–47) methylated sites of the gene KLHDC9; (48) methylated site of the gene PLAU; (49–57) methylated sites of the gene S1PR1
The causes of cancer are due to mutations of key proteins involved in cell cycle regulation, DNA rep...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
Despite of intense research in early cancer detection, there is a lack of biomarkers for the reliabl...
Additional file 3. The proteinâprotein interaction network of 118 methylation-driven genes and the...
Additional file 4. Pathway analysis of methylation-driven genes associated with LUAD (Pâ<â0.05)
Additional file 6: Table S6. Gene expression datasets with paired cancer-normal lung tissues
Introduction. Lung adenocarcinoma (LAC) is the most frequent type of lung cancer and has a high meta...
Additional file 3: Table S3. The frequencies of DM CpG sites in the 539 lung adenocarcinoma samples ...
Lung adenocarcinoma (LUAD) is the most frequent pathological type of lung cancer that has a poor pro...
Abstract Background As one of the most common malignant tumors in humans, lung cancer has experience...
<div><p>The aim of this study was to clarify the significance of DNA methylation alterations at prec...
The aim of this study was to clarify the significance of DNA methylation alterations at precancerous...
AbstractEpigenetic changes, including DNA methylation, are a common finding in cancer. In lung cance...
Accumulating evidence has proved that aberrant methylation of enhancers plays regulatory roles in ge...
Figure S1. Differential methylated sites. Representation of the amount of methylated sites per gene ...
The causes of cancer are due to mutations of key proteins involved in cell cycle regulation, DNA rep...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
Despite of intense research in early cancer detection, there is a lack of biomarkers for the reliabl...
Additional file 3. The proteinâprotein interaction network of 118 methylation-driven genes and the...
Additional file 4. Pathway analysis of methylation-driven genes associated with LUAD (Pâ<â0.05)
Additional file 6: Table S6. Gene expression datasets with paired cancer-normal lung tissues
Introduction. Lung adenocarcinoma (LAC) is the most frequent type of lung cancer and has a high meta...
Additional file 3: Table S3. The frequencies of DM CpG sites in the 539 lung adenocarcinoma samples ...
Lung adenocarcinoma (LUAD) is the most frequent pathological type of lung cancer that has a poor pro...
Abstract Background As one of the most common malignant tumors in humans, lung cancer has experience...
<div><p>The aim of this study was to clarify the significance of DNA methylation alterations at prec...
The aim of this study was to clarify the significance of DNA methylation alterations at precancerous...
AbstractEpigenetic changes, including DNA methylation, are a common finding in cancer. In lung cance...
Accumulating evidence has proved that aberrant methylation of enhancers plays regulatory roles in ge...
Figure S1. Differential methylated sites. Representation of the amount of methylated sites per gene ...
The causes of cancer are due to mutations of key proteins involved in cell cycle regulation, DNA rep...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
Despite of intense research in early cancer detection, there is a lack of biomarkers for the reliabl...