(a) The M1 zebrafish embryo without rescue. (b) The M1 zebrafish with rescue. (c) The M2 zebrafish without rescue. (d) The M2 zebrafish with rescue. (e) The comparison of heart looping in zebrafish embryos at 72 hpf, among WT, WT + injection control, M1, M1 + pr72 mRNA, M2 and M2 + pr72 mRNA groups. WT, wild type zebrafish embryos; WT + injection control, wild type zebrafish embryos injected with pr72 mRNA; M1, mutant zebrafish embryo without rescue; M1+ pr72 mRNA, the mutant zebrafish with rescue; M2, mutant zebrafish without rescue; M2 + pr72 mRNA, mutant zebrafish with rescue. The numbers of fish are shown in the columns. Data are expressed as percentages. *, p p < 0.01, unpaired student t test. The experiment was carried out in triplica...
The zebrafish (Danio rerio) has emerged as one of the primary experimental models of developmental c...
<p><b>(A, B)</b> Lateral view of <i>whz</i> mutant embryos control-injected with KCl <b>(A)</b> and ...
<p>For rescue study, the <i>Nkx2.5</i> mRNA was co-injected with Nkx2.7-MO into embryos derived from...
(A) Different types of zebrafish heart are shown in Tg (cmlc2: eCherry) morphants in ventral view: d...
(A) Tg(flk1:EGFP) zebrafish embryos injected with morpholinos (MOs) for novel candidate genes for CA...
<p>To examine organ laterality defects, zebrafish embryos were examined for changes in heart looping...
<p>Morpholino knockdown of rbp7a results in randomized heart looping. <i>cmlc2</i> expression at 38 ...
<p>A) Visual classification of malformations depending on the severity of the defect: Level 1, wild ...
<p>Wildtype embryos were incubated in water containing vehicle (0.1% DMSO), estradiol (3.67 μM, ER/G...
The zebrafish (Danio rerio) is a new animal model for cardiac research. Zebrafish possessing a green...
<p>(A) The morphologies of zebrafish morphants at 72 hpf. Note that the morphants of <i>ttc4</i>, <i...
<p>Eight nanograms of MO were injected into one-cell stage embryos derived from transgenic line Tg (...
<p>(A) RT-PCR analysis of zebrafish <i>kif20a</i> gene expression during early stages. <i>Gapdh</i> ...
Over the past decade, the zebrafish has become an increasingly popular animal model for the study of...
The zebrafish (Danio rerio) has emerged as one of the primary experimental models of developmental c...
The zebrafish (Danio rerio) has emerged as one of the primary experimental models of developmental c...
<p><b>(A, B)</b> Lateral view of <i>whz</i> mutant embryos control-injected with KCl <b>(A)</b> and ...
<p>For rescue study, the <i>Nkx2.5</i> mRNA was co-injected with Nkx2.7-MO into embryos derived from...
(A) Different types of zebrafish heart are shown in Tg (cmlc2: eCherry) morphants in ventral view: d...
(A) Tg(flk1:EGFP) zebrafish embryos injected with morpholinos (MOs) for novel candidate genes for CA...
<p>To examine organ laterality defects, zebrafish embryos were examined for changes in heart looping...
<p>Morpholino knockdown of rbp7a results in randomized heart looping. <i>cmlc2</i> expression at 38 ...
<p>A) Visual classification of malformations depending on the severity of the defect: Level 1, wild ...
<p>Wildtype embryos were incubated in water containing vehicle (0.1% DMSO), estradiol (3.67 μM, ER/G...
The zebrafish (Danio rerio) is a new animal model for cardiac research. Zebrafish possessing a green...
<p>(A) The morphologies of zebrafish morphants at 72 hpf. Note that the morphants of <i>ttc4</i>, <i...
<p>Eight nanograms of MO were injected into one-cell stage embryos derived from transgenic line Tg (...
<p>(A) RT-PCR analysis of zebrafish <i>kif20a</i> gene expression during early stages. <i>Gapdh</i> ...
Over the past decade, the zebrafish has become an increasingly popular animal model for the study of...
The zebrafish (Danio rerio) has emerged as one of the primary experimental models of developmental c...
The zebrafish (Danio rerio) has emerged as one of the primary experimental models of developmental c...
<p><b>(A, B)</b> Lateral view of <i>whz</i> mutant embryos control-injected with KCl <b>(A)</b> and ...
<p>For rescue study, the <i>Nkx2.5</i> mRNA was co-injected with Nkx2.7-MO into embryos derived from...