<i>In-silico</i> analysis of equine microRNAs targets.
- Lucia Natalia Moro (2136490)
- Guadalupe Amin (6037844)
- Veronica Furmento (6037847)
- Ariel Waisman (484621)
- Ximena Garate (6037850)
- Gabriel Neiman (6037853)
- Alejandro La Greca (6037856)
- Natalia Lucia Santín Velazque (6037859)
- Carlos Luzzani (484623)
- Gustavo E. Sevlever (6037862)
- Gabriel Vichera (3216861)
- Santiago Gabriel Miriuka (439718)
Publication date
December 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
The green bars and the black zones represent the homology between sequences. a) Comparison between equine miR-302/367 cluster (eca-miR-302/367) and human miR-302/367 cluster (hsa-miR-302/367) in the genome. In orange are the different microRNAs positioned in the cluster. Below this alignment, the seed sequence of the miR-302 family is aligned to the 3‘UTR of 4 mRNAs in the equine (CDK2, E2F1, RHOC and CYCLIN D). b) Seed alignment of the differentiation-related microRNAs miR-9, miR-96 and miR-145, to the 3‘UTR of the equine mRNAs HES1, PAX6 and KLF4 and OCT-4, respectively.</p
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