Total genetic heritability was set as 50% and 70% for two different sets of simulated data. 5%-contaminated data was added to phenotypes to investigate the robustness property of the approaches. (A) Analysis results in the case of 50% genetic heritability and no outlying observation; (B) analysis results in the case of 50% genetic heritability and 5% outlying observations; (C) Analysis results in the case of 70% genetic heritability and no outlying observation; (D) analysis results in the case of 70% genetic heritability and 5% outlying observations. Threshold for each method were calculated using permutation test with 1000 replicates.</p
The variance explained by genetic variants as identified in (genome-wide) genetic association studie...
Background The variance explained by genetic variants as identified in (genome-wide) genetic associa...
BACKGROUND: The variance explained by genetic variants as identified in (genome-wide) genetic associ...
(A) Analysis results in absence of outliers; (B) analysis results in presence of 5% outliers. Thresh...
Simulation was used to study the power of detection of a fairly young (mutation occurred 50 generati...
<p>The vertical dashed line gives the simulated heritability (QTL, MRK, MRK+QTL indicate whether QTL...
Abstract Background: Recent developments in genetic technology and methodology enable accurate detec...
<p>Each plot presents results for one simulation scenario (5/10K 10 thousand LD blocks with 5 loci e...
The aim of this study was to explore, by computer simulation, the mapping of QTLs in a realistic but...
The aim of this study was to explore, by computer simulation, the mapping of QTLs in a realistic but...
The aim of this study was to explore, by computer simulation, the mapping of QTLs in a realistic but...
Theoretical comparisons for quantitative trait loci (QTL) mapping properties were conducted among si...
A number of recent works have introduced statistical methods for detecting genetic loci that affect ...
The aim of this study was to explore, by computer simulation, the mapping of QTLs in a realistic but...
Quantitative trait locus (QTL) mapping studies often employ segregating generations derived from a c...
The variance explained by genetic variants as identified in (genome-wide) genetic association studie...
Background The variance explained by genetic variants as identified in (genome-wide) genetic associa...
BACKGROUND: The variance explained by genetic variants as identified in (genome-wide) genetic associ...
(A) Analysis results in absence of outliers; (B) analysis results in presence of 5% outliers. Thresh...
Simulation was used to study the power of detection of a fairly young (mutation occurred 50 generati...
<p>The vertical dashed line gives the simulated heritability (QTL, MRK, MRK+QTL indicate whether QTL...
Abstract Background: Recent developments in genetic technology and methodology enable accurate detec...
<p>Each plot presents results for one simulation scenario (5/10K 10 thousand LD blocks with 5 loci e...
The aim of this study was to explore, by computer simulation, the mapping of QTLs in a realistic but...
The aim of this study was to explore, by computer simulation, the mapping of QTLs in a realistic but...
The aim of this study was to explore, by computer simulation, the mapping of QTLs in a realistic but...
Theoretical comparisons for quantitative trait loci (QTL) mapping properties were conducted among si...
A number of recent works have introduced statistical methods for detecting genetic loci that affect ...
The aim of this study was to explore, by computer simulation, the mapping of QTLs in a realistic but...
Quantitative trait locus (QTL) mapping studies often employ segregating generations derived from a c...
The variance explained by genetic variants as identified in (genome-wide) genetic association studie...
Background The variance explained by genetic variants as identified in (genome-wide) genetic associa...
BACKGROUND: The variance explained by genetic variants as identified in (genome-wide) genetic associ...