Additional file 2: of MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cells

Figure S2. Factors secreted by RENCA macrobeads alter the transcription factor activity of MEF2 in DU145 cells. MEF2 reporter activity in DU145 cells exposed to 5-day RENCA macrobead-conditioned media. Reporter activity in response to naïve media was used as a control. Fold-change was calculated for each sample relative to the naïve media sample. Each column represents the mean (n = 6–8) ± SD (primary axis). Mean inhibitory response of RENCA macrobeads on freely growing DU145 cells; red circles (n = 3) ± SD (secondary axis). (PDF 24 kb