Additional file 1: of MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cells

Figure S1. MEF2 isoform expression in RENCA cells following transfection with MEF2 isoform-specific siRNA. Expression of MEF2a, MEF2b and MEF2d from RENCA cells transiently transfected with two-rounds of 1 μM non-targeting siRNA, MEF2a, MEF2b, MEF2d or combined MEF2a, b and d siRNAs (MEF2 pool) was assessed (a) at the beginning (day 0) of the growth inhibition assay and following culture for 5 days in (b) naïve media or (c) together with > 18 wk. RENCA macrobeads in a cell culture insert system. Untreated RENCA cells were included as a non-transfection control. Each column represents the mean (n = 3) ± SD. Relative expression is calculated as a ratio, with expression levels for the specified condition divided by the expression of the non-targeting siRNA for each isoform. (PDF 37 kb