Background: HOXA10 is a key transcriptional factor that regulates testis development as reported from previous transgenic mouse models and human inherited diseases. However, whether it also plays important roles in promoting the development of testicular cancer is not well-understood.Objective: To study the expression of HOXA10 and its regulated signaling pathways in testicular cancers.Design, Setting, and Participants: A tissue microarray was constructed with benign and cancerous testis. TCam2, NT-2, and NCCIT cell models were applied in this study.Intervention: Immunohistochemistry and immunofluorescence were performed to measure the expression and cellular localization of HOXA10 in testicular cancer tissues and cell models. Cell prolifer...
International audienceABSTRACT: BACKGROUND: HOX genes encode a family of homeodomain-containing tran...
Abstract. HOX-proteins are master regulators of embryogenesis. They determine the body plan along th...
Background: The expression of human germline genes is restricted to the germ cells of the gonads, wh...
Background: HOXA10 is a key transcriptional factor that regulates testis development as reported fro...
Background: HOXA10 is a key transcriptional factor that regulates testis development as reported fro...
Homeobox (HOX) A10 is essential for fertility as demonstrated in transgenic mice, specifically affec...
Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer death among women in the United...
Background: The Cancer/Testis Antigens (CTAs) are a heterogeneous group of proteins whose expression...
Testicular cancer (TC) is one of the most common neoplasms that occurs in male and includes germ cel...
Cancer Stem-like Cells (CSC) are believed to be responsible for local relapse and metastasis of tumo...
BackgroundTesticular germ cell tumor (TGCT) is the most common tumor in young men, but molecular sig...
Genito-urinary malignancies (prostate, bladder, renal and testicular cancers) rank high among human ...
<p><b>a</b> The prediction of the binding between miR-10a and HOXA1 by Pictar. <b>b</b> HOXA1 protei...
BACKGROUND: In male mice, targeted disruption of the homeobox gene hoxa10 causes cryptorchidism and...
Bona fide germline genes have expression restricted to the germ cells of the gonads. Testis-specific...
International audienceABSTRACT: BACKGROUND: HOX genes encode a family of homeodomain-containing tran...
Abstract. HOX-proteins are master regulators of embryogenesis. They determine the body plan along th...
Background: The expression of human germline genes is restricted to the germ cells of the gonads, wh...
Background: HOXA10 is a key transcriptional factor that regulates testis development as reported fro...
Background: HOXA10 is a key transcriptional factor that regulates testis development as reported fro...
Homeobox (HOX) A10 is essential for fertility as demonstrated in transgenic mice, specifically affec...
Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer death among women in the United...
Background: The Cancer/Testis Antigens (CTAs) are a heterogeneous group of proteins whose expression...
Testicular cancer (TC) is one of the most common neoplasms that occurs in male and includes germ cel...
Cancer Stem-like Cells (CSC) are believed to be responsible for local relapse and metastasis of tumo...
BackgroundTesticular germ cell tumor (TGCT) is the most common tumor in young men, but molecular sig...
Genito-urinary malignancies (prostate, bladder, renal and testicular cancers) rank high among human ...
<p><b>a</b> The prediction of the binding between miR-10a and HOXA1 by Pictar. <b>b</b> HOXA1 protei...
BACKGROUND: In male mice, targeted disruption of the homeobox gene hoxa10 causes cryptorchidism and...
Bona fide germline genes have expression restricted to the germ cells of the gonads. Testis-specific...
International audienceABSTRACT: BACKGROUND: HOX genes encode a family of homeodomain-containing tran...
Abstract. HOX-proteins are master regulators of embryogenesis. They determine the body plan along th...
Background: The expression of human germline genes is restricted to the germ cells of the gonads, wh...