Additional file 4: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Additional file 2: of EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC

Yalei Yin (5347217)
Mingju Sun (6370715)
Xi Zhan (220567)
Changqing Wu (6370718)
Pengyu Geng (6370721)
Xiaoyan Sun (28501)
Yunsong Wu (6370724)
Shuijun Zhang (294875)
Jianhua Qin (374312)
Zhengping Zhuang (63356)
Yang Liu (4829)

February 2019

Figure S2. BET inhibitor inhibited tumor growth more potently than sorafenib in MYC- positive HCC ce...

Additional file 1: of 14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

Jia Song (495396)
Xiaochao Zhang (6046529)
Zhibin Liao (6173411)
Huifang Liang (781781)
Liang Chu (126831)
Wei Dong (6479)
Xuewu Zhang (2310436)
Qianyun Ge (6173414)
Qiumeng Liu (6173417)
Pan Fan (6173420)
Zhanguo Zhang (3138240)
Bixiang Zhang (745204)

January 2019

Table S1. Primers for shRNA lentiviral constructs; Table S2. siRNA target sequences; Table S3. The s...

Additional file 4: of Ajuba inhibits hepatocellular carcinoma cell growth via targeting of β-catenin and YAP signaling and is regulated by E3 ligase Hakai through neddylation

Min Liu (45756)
Ke Jiang (193253)
Guibin Lin (5534402)
Peng Liu (120506)
Yumei Yan (690276)
Tian Ye (1907803)
Gang Yao (31248)
Martin Barr (4458760)
Dapeng Liang (151334)
Yang Wang (5921)
Peng Gong (69507)
Songshu Meng (712742)
Haozhe Piao (5555666)

July 2018

Figure S4. Hakai mediates Ajuba degradation via neddylation. (A) Immunoblot analysis and quantificat...

Additional file 3: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Bin Dai (320307)
Xuan Zhang (56049)
Runze Shang (6085088)
Jianlin Wang (1313004)
Xisheng Yang (6085091)
Hong Zhang (25820)
Qi Liu (33068)
Desheng Wang (196022)
Lin Wang (11986)
Kefeng Dou (174028)

December 2018

Figure S1. Efficacy of ARHGAP11A knockdown in Hep3B and MHCC97-H cells. Columns, mean (n = 3, in tri...

Additional file 6: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Bin Dai (320307)
Xuan Zhang (56049)
Runze Shang (6085088)
Jianlin Wang (1313004)
Xisheng Yang (6085091)
Hong Zhang (25820)
Qi Liu (33068)
Desheng Wang (196022)
Lin Wang (11986)
Kefeng Dou (174028)

December 2018

Figure S4. Identified proteinsâ ubiquitination peptide interacted with ARHGAP11A in HCC (nâ=â3...

Additional file 5: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Bin Dai (320307)
Xuan Zhang (56049)
Runze Shang (6085088)
Jianlin Wang (1313004)
Xisheng Yang (6085091)
Hong Zhang (25820)
Qi Liu (33068)
Desheng Wang (196022)
Lin Wang (11986)
Kefeng Dou (174028)

December 2018

Figure S3. Expression of P53 protein in Scrambled (NC) and ARHGAP11A-Sh transfected Hep3B and MHCC97...

Additional file 1: of Histone deacetylase inhibitors suppress aggressiveness of head and neck squamous cell carcinoma via histone acetylation-independent blockade of the EGFR-Arf1 axis

Leilei He (3093528)
Lixia Gao (3626891)
Chloe Shay (4104376)
Liwei Lang (577095)
Fenglin Lv (5258141)
Yong Teng (205028)

February 2019

Figure S1. The effects of expression of Arf1DN and Arf1CA on HNSCC cell proliferation measured by MT...

Additional file 1: of Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells

Halina Was (94523)
Sylwia Krol (6241592)
Dante Rotili (462382)
Antonello Mai (205768)
Bartosz Wojtas (6241595)
Bozena Kaminska (65469)
Marta Maleszewska (6241598)

January 2019

Figure S1. (A) Densitometry analysis of western blot shows efficacy of HDAC 1 and HDAC 2 knockdown a...

Additional file 4: of EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC

Yalei Yin (5347217)
Mingju Sun (6370715)
Xi Zhan (220567)
Changqing Wu (6370718)
Pengyu Geng (6370721)
Xiaoyan Sun (28501)
Yunsong Wu (6370724)
Shuijun Zhang (294875)
Jianhua Qin (374312)
Zhengping Zhuang (63356)
Yang Liu (4829)

February 2019

Figure S4. JQ1 significantly induced apoptosis in MYC-positive HCC cells. HCC cells were treated wit...

Additional file 4: Figure S4. of Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death

Dave Augeri (3764338)
Elaine Langenfeld (402034)
Monica Castle (3764335)
John Gilleran (3764332)
John Langenfeld (402036)

April 2016

MEK-1/2 and Src signaling do not cause feedback activation of Id1 following inhibition of BMP signal...

Additional file 3: of PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cells

Linglong Yin (5520650)
Youhong Liu (112509)
Yuchong Peng (5520647)
Yongbo Peng (5520644)
Xiaohui Yu (303050)
Yingxue Gao (5520632)
Bowen Yuan (5520641)
Qianling Zhu (5520635)
Tuoyu Cao (5520638)
Leye He (639328)
Zhicheng Gong (475095)
Lunquan Sun (339841)
Xuegong Fan (142698)
Xiong Li (112522)

July 2018

Figure S2. (A) LNCaP, PC-3, CWR22Rv1 and C4–2 cells were treated with SAHA and veliparib alone or in...

Additional file 1: of Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

Lehe Yang (328695)
Shichong Lin (6258605)
Yanting Kang (6258608)
Youqun Xiang (6113663)
Lingyuan Xu (6258611)
Jifa Li (6258614)
Xuanxuan Dai (4421281)
Guang Liang (206236)
Xiaoying Huang (328697)
Chengguang Zhao (4221556)

January 2019

Figure S1. Rhein inhibits P-STAT3 and induces apoptosis in pancreatic cancer cell. (A) The STAT3 pla...

Additional file 11: of AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity

Sanja Brolih (4913359)
Scott Parks (4913353)
Valérie Vial (4913356)
Jérôme Durivault (2552887)
Livio Mostosi (4913350)
Jacques Pouysségur (185906)
Gilles Pagès (185905)
Vincent Picco (4913347)

March 2018

Figure S2 Analysis of e-cadherin expression and localization by immunofluorescence in CAL33 cells. I...

Additional file 2: of IΚΚε cooperates with either MEK or non-canonical NF-kB driving growth of triple-negative breast cancer cells in different contexts

Carrie House (267929)
Valentina Grajales (5290823)
Michelle Ozaki (5290826)
Elizabeth Jordan (3540098)
Helmae Wubneh (5290829)
Danielle Kimble (5290835)
Jana James (5290832)
Marianne Kim (3540086)
Christina Annunziata (3540092)

May 2018

Figure S1. Protein activity suppressed by inhibitors. Western blot quantification and short time poi...

Additional file 7: of ARNTL hypermethylation promotes tumorigenesis and inhibits cisplatin sensitivity by activating CDK5 transcription in nasopharyngeal carcinoma

Hao Peng (231482)
Jian Zhang (1682)
Pan-Pan Zhang (3278736)
Lei Chen (54296)
Ling-Long Tang (462998)
Xiao-Jing Yang (580274)
Qing-Mei He (545472)
Xin Wen (470639)
Ying Sun (23237)
Na Liu (102929)
Ying-Qin Li (545471)
Jun Ma (9393)

January 2019

Figure S6. ARNTL affect the proliferation ability of NP69 cells. (A) Western blot assay found that C...

Additional file 2: of EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC

Yalei Yin (5347217)
Mingju Sun (6370715)
Xi Zhan (220567)
Changqing Wu (6370718)
Pengyu Geng (6370721)
Xiaoyan Sun (28501)
Yunsong Wu (6370724)
Shuijun Zhang (294875)
Jianhua Qin (374312)
Zhengping Zhuang (63356)
Yang Liu (4829)

February 2019

Figure S2. BET inhibitor inhibited tumor growth more potently than sorafenib in MYC- positive HCC ce...

Additional file 1: of 14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

Jia Song (495396)
Xiaochao Zhang (6046529)
Zhibin Liao (6173411)
Huifang Liang (781781)
Liang Chu (126831)
Wei Dong (6479)
Xuewu Zhang (2310436)
Qianyun Ge (6173414)
Qiumeng Liu (6173417)
Pan Fan (6173420)
Zhanguo Zhang (3138240)
Bixiang Zhang (745204)

January 2019

Table S1. Primers for shRNA lentiviral constructs; Table S2. siRNA target sequences; Table S3. The s...

Additional file 4: of Ajuba inhibits hepatocellular carcinoma cell growth via targeting of β-catenin and YAP signaling and is regulated by E3 ligase Hakai through neddylation

Min Liu (45756)
Ke Jiang (193253)
Guibin Lin (5534402)
Peng Liu (120506)
Yumei Yan (690276)
Tian Ye (1907803)
Gang Yao (31248)
Martin Barr (4458760)
Dapeng Liang (151334)
Yang Wang (5921)
Peng Gong (69507)
Songshu Meng (712742)
Haozhe Piao (5555666)

July 2018

Figure S4. Hakai mediates Ajuba degradation via neddylation. (A) Immunoblot analysis and quantificat...

Additional file 3: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Bin Dai (320307)
Xuan Zhang (56049)
Runze Shang (6085088)
Jianlin Wang (1313004)
Xisheng Yang (6085091)
Hong Zhang (25820)
Qi Liu (33068)
Desheng Wang (196022)
Lin Wang (11986)
Kefeng Dou (174028)

December 2018

Figure S1. Efficacy of ARHGAP11A knockdown in Hep3B and MHCC97-H cells. Columns, mean (n = 3, in tri...

Additional file 6: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Bin Dai (320307)
Xuan Zhang (56049)
Runze Shang (6085088)
Jianlin Wang (1313004)
Xisheng Yang (6085091)
Hong Zhang (25820)
Qi Liu (33068)
Desheng Wang (196022)
Lin Wang (11986)
Kefeng Dou (174028)

December 2018

Figure S4. Identified proteinsâ ubiquitination peptide interacted with ARHGAP11A in HCC (nâ=â3...

Additional file 5: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Bin Dai (320307)
Xuan Zhang (56049)
Runze Shang (6085088)
Jianlin Wang (1313004)
Xisheng Yang (6085091)
Hong Zhang (25820)
Qi Liu (33068)
Desheng Wang (196022)
Lin Wang (11986)
Kefeng Dou (174028)

December 2018

Figure S3. Expression of P53 protein in Scrambled (NC) and ARHGAP11A-Sh transfected Hep3B and MHCC97...

Additional file 1: of Histone deacetylase inhibitors suppress aggressiveness of head and neck squamous cell carcinoma via histone acetylation-independent blockade of the EGFR-Arf1 axis

Leilei He (3093528)
Lixia Gao (3626891)
Chloe Shay (4104376)
Liwei Lang (577095)
Fenglin Lv (5258141)
Yong Teng (205028)

February 2019

Figure S1. The effects of expression of Arf1DN and Arf1CA on HNSCC cell proliferation measured by MT...

Additional file 1: of Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells

Halina Was (94523)
Sylwia Krol (6241592)
Dante Rotili (462382)
Antonello Mai (205768)
Bartosz Wojtas (6241595)
Bozena Kaminska (65469)
Marta Maleszewska (6241598)

January 2019

Figure S1. (A) Densitometry analysis of western blot shows efficacy of HDAC 1 and HDAC 2 knockdown a...

Additional file 4: of EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC

Yalei Yin (5347217)
Mingju Sun (6370715)
Xi Zhan (220567)
Changqing Wu (6370718)
Pengyu Geng (6370721)
Xiaoyan Sun (28501)
Yunsong Wu (6370724)
Shuijun Zhang (294875)
Jianhua Qin (374312)
Zhengping Zhuang (63356)
Yang Liu (4829)

February 2019

Figure S4. JQ1 significantly induced apoptosis in MYC-positive HCC cells. HCC cells were treated wit...

Additional file 4: Figure S4. of Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death

Dave Augeri (3764338)
Elaine Langenfeld (402034)
Monica Castle (3764335)
John Gilleran (3764332)
John Langenfeld (402036)

April 2016

MEK-1/2 and Src signaling do not cause feedback activation of Id1 following inhibition of BMP signal...

Additional file 3: of PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cells

Linglong Yin (5520650)
Youhong Liu (112509)
Yuchong Peng (5520647)
Yongbo Peng (5520644)
Xiaohui Yu (303050)
Yingxue Gao (5520632)
Bowen Yuan (5520641)
Qianling Zhu (5520635)
Tuoyu Cao (5520638)
Leye He (639328)
Zhicheng Gong (475095)
Lunquan Sun (339841)
Xuegong Fan (142698)
Xiong Li (112522)

July 2018

Figure S2. (A) LNCaP, PC-3, CWR22Rv1 and C4–2 cells were treated with SAHA and veliparib alone or in...

Additional file 1: of Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

Lehe Yang (328695)
Shichong Lin (6258605)
Yanting Kang (6258608)
Youqun Xiang (6113663)
Lingyuan Xu (6258611)
Jifa Li (6258614)
Xuanxuan Dai (4421281)
Guang Liang (206236)
Xiaoying Huang (328697)
Chengguang Zhao (4221556)

January 2019

Figure S1. Rhein inhibits P-STAT3 and induces apoptosis in pancreatic cancer cell. (A) The STAT3 pla...

Additional file 11: of AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity

Sanja Brolih (4913359)
Scott Parks (4913353)
Valérie Vial (4913356)
Jérôme Durivault (2552887)
Livio Mostosi (4913350)
Jacques Pouysségur (185906)
Gilles Pagès (185905)
Vincent Picco (4913347)

March 2018

Figure S2 Analysis of e-cadherin expression and localization by immunofluorescence in CAL33 cells. I...

Additional file 2: of IΚΚε cooperates with either MEK or non-canonical NF-kB driving growth of triple-negative breast cancer cells in different contexts

Carrie House (267929)
Valentina Grajales (5290823)
Michelle Ozaki (5290826)
Elizabeth Jordan (3540098)
Helmae Wubneh (5290829)
Danielle Kimble (5290835)
Jana James (5290832)
Marianne Kim (3540086)
Christina Annunziata (3540092)

May 2018

Figure S1. Protein activity suppressed by inhibitors. Western blot quantification and short time poi...

Additional file 7: of ARNTL hypermethylation promotes tumorigenesis and inhibits cisplatin sensitivity by activating CDK5 transcription in nasopharyngeal carcinoma

Hao Peng (231482)
Jian Zhang (1682)
Pan-Pan Zhang (3278736)
Lei Chen (54296)
Ling-Long Tang (462998)
Xiao-Jing Yang (580274)
Qing-Mei He (545472)
Xin Wen (470639)
Ying Sun (23237)
Na Liu (102929)
Ying-Qin Li (545471)
Jun Ma (9393)

January 2019

Figure S6. ARNTL affect the proliferation ability of NP69 cells. (A) Western blot assay found that C...

Additional file 2: of EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC

Yalei Yin (5347217)
Mingju Sun (6370715)
Xi Zhan (220567)
Changqing Wu (6370718)
Pengyu Geng (6370721)
Xiaoyan Sun (28501)
Yunsong Wu (6370724)
Shuijun Zhang (294875)
Jianhua Qin (374312)
Zhengping Zhuang (63356)
Yang Liu (4829)

February 2019

Figure S2. BET inhibitor inhibited tumor growth more potently than sorafenib in MYC- positive HCC ce...

Additional file 1: of 14–3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling

Jia Song (495396)
Xiaochao Zhang (6046529)
Zhibin Liao (6173411)
Huifang Liang (781781)
Liang Chu (126831)
Wei Dong (6479)
Xuewu Zhang (2310436)
Qianyun Ge (6173414)
Qiumeng Liu (6173417)
Pan Fan (6173420)
Zhanguo Zhang (3138240)
Bixiang Zhang (745204)

January 2019

Table S1. Primers for shRNA lentiviral constructs; Table S2. siRNA target sequences; Table S3. The s...

Additional file 4: of Ajuba inhibits hepatocellular carcinoma cell growth via targeting of β-catenin and YAP signaling and is regulated by E3 ligase Hakai through neddylation

Min Liu (45756)
Ke Jiang (193253)
Guibin Lin (5534402)
Peng Liu (120506)
Yumei Yan (690276)
Tian Ye (1907803)
Gang Yao (31248)
Martin Barr (4458760)
Dapeng Liang (151334)
Yang Wang (5921)
Peng Gong (69507)
Songshu Meng (712742)
Haozhe Piao (5555666)

July 2018

Figure S4. Hakai mediates Ajuba degradation via neddylation. (A) Immunoblot analysis and quantificat...

Additional file 4: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Abstract

Extracted data

Additional file 4: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

Abstract

Extracted data

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