Figure S1. Location distribution of clinical centers in the Autism Clinical and Genetic Resources in China (ACGC). (PDF 1173 kb
High- Probability Risk ASD Gene Set. Table of seventy-six genes from AutDB determined to be âproba...
Score distributions of the RSM and IS subcategories in the AGRE cohort. (DOCX 60 kb
Figure S8. Multiple-hit model for ASD excluding DNM cases. Shown are comparisons of autism probands ...
Figure S2. QC of MIPs cohort. QC analysis of the percentage of MIPs with at least eight reads per sa...
Figure S4. Distribution of DNMs for SCN2A and CHD8. LGD (red) and missense (blue) DNMs with respect ...
Data 5. Summary of clinical information for some patients with DNMs. (XLSX 19 kb
Figure S9. Parent carriers of CHD8 LGD mutations show autistic traits. The density plots are based o...
Figure S5. Distribution of missense mutations in SCN2A and CHD8. a. Missense DNMs in SCN2A are mainl...
Table S1. Sample description and scores on primary measures. Table S2. General information of gene t...
Figure S3. Fraction of target based on >â8-fold sequence coverage by gene. Box and whisker plots s...
Regions of variants of uncertain clinical significance found in our cohort. Genomic coordinates were...
Two-dimensional Multidimensional Scaling (MDS) plot of the AGRE population. (DOCX 88 kb
Abstract Background We previously performed targeted sequencing of autism risk genes in probands fro...
List of candidate autism genes. Genes listed were used to produce Fig. 5. (XLS 102 kb
Moderate- Probability Risk ASD Gene Set. Table of 292 genes from AutDB categorized as possibly damag...
High- Probability Risk ASD Gene Set. Table of seventy-six genes from AutDB determined to be âproba...
Score distributions of the RSM and IS subcategories in the AGRE cohort. (DOCX 60 kb
Figure S8. Multiple-hit model for ASD excluding DNM cases. Shown are comparisons of autism probands ...
Figure S2. QC of MIPs cohort. QC analysis of the percentage of MIPs with at least eight reads per sa...
Figure S4. Distribution of DNMs for SCN2A and CHD8. LGD (red) and missense (blue) DNMs with respect ...
Data 5. Summary of clinical information for some patients with DNMs. (XLSX 19 kb
Figure S9. Parent carriers of CHD8 LGD mutations show autistic traits. The density plots are based o...
Figure S5. Distribution of missense mutations in SCN2A and CHD8. a. Missense DNMs in SCN2A are mainl...
Table S1. Sample description and scores on primary measures. Table S2. General information of gene t...
Figure S3. Fraction of target based on >â8-fold sequence coverage by gene. Box and whisker plots s...
Regions of variants of uncertain clinical significance found in our cohort. Genomic coordinates were...
Two-dimensional Multidimensional Scaling (MDS) plot of the AGRE population. (DOCX 88 kb
Abstract Background We previously performed targeted sequencing of autism risk genes in probands fro...
List of candidate autism genes. Genes listed were used to produce Fig. 5. (XLS 102 kb
Moderate- Probability Risk ASD Gene Set. Table of 292 genes from AutDB categorized as possibly damag...
High- Probability Risk ASD Gene Set. Table of seventy-six genes from AutDB determined to be âproba...
Score distributions of the RSM and IS subcategories in the AGRE cohort. (DOCX 60 kb
Figure S8. Multiple-hit model for ASD excluding DNM cases. Shown are comparisons of autism probands ...