Additional file 14: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang
Yanting Zhou
Guirong Sun
Kui Li
Zhuanjian Li
Aru Su
Xiaojun Liu
Guoxi Li
Ruirui Jiang
Ruili Han
Yadong Tian
Xiangtao Kang
Fengbin Yan

December 2018

Abstract Background The molecular mechanisms underlying stress-influenced immune function of chicken...

Additional file 4: of Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

Melissa Monson (5704835)
Angelica Van Goor (3569357)
Christopher Ashwell (3569354)
Michael Persia (3569348)
Max Rothschild (3569351)
Carl Schmidt (3159513)
Susan Lamont (340168)

August 2018

Correlations between log2FC from RNA-seq and Biomark qPCR. Compares log2FC from RNA-seq and qPCR for...

Additional file 3: of Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

Melissa Monson (5704835)
Angelica Van Goor (3569357)
Christopher Ashwell (3569354)
Michael Persia (3569348)
Max Rothschild (3569351)
Carl Schmidt (3159513)
Susan Lamont (340168)

August 2018

Significant differential expression in each comparison between treatments or chicken lines. Contains...

Additional file 8: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S6. The correlation coefficient between receptor genes expression and ligand genes expression ...

Additional file 4: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S2. The gene expression level of the two groups. Sheet 1 showed the top 10 highest expression ...

Additional file 1: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S1. Characteristics of the reads from bursa of Fabricius libraries obtained from 2 groups. 1Mu...

Additional file 7: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S5. The KEGG enrichments of the differentially expressed genes of the C_B group and B_B group....

Additional file 3: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Figure S2. Venn diagram of global genes expressed in two groups. Red indicates the genes specific ex...

Additional file 6: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S4. The GO enrichment of SDEGs of the C_B group and B_B group. Sheet 1 showed the top 30 most ...

Additional file 5: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S3. The DEGs in the C_B group compared with the B_B group. Sheet 1 showed the SDEGs, sheet 2 s...

Additional file 9: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S7. Protein-protein interaction network for all SDEGs. Sheet 1 showed the interactions with a ...

Additional file 13: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S9. Effects of CORT treatment on immune related indexes of chickens. Data are shown as the mea...

Additional file 11: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Figure S4. 19 modules of the protein-protein interaction network with node > 3 and a MCODE score > 3...

Additional file 12: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S8. Effects of CORT treatment on the serum biochemical indexes of chickens. Data are shown as ...

Additional file 8: of Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

Melissa Monson (5704835)
Angelica Van Goor (3569357)
Christopher Ashwell (3569354)
Michael Persia (3569348)
Max Rothschild (3569351)
Carl Schmidt (3159513)
Susan Lamont (340168)

August 2018

Primers for qPCR validation of differential expression using the Biomark HD system. (DOCX 18 kb

Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang
Yanting Zhou
Guirong Sun
Kui Li
Zhuanjian Li
Aru Su
Xiaojun Liu
Guoxi Li
Ruirui Jiang
Ruili Han
Yadong Tian
Xiangtao Kang
Fengbin Yan

December 2018

Abstract Background The molecular mechanisms underlying stress-influenced immune function of chicken...

Additional file 4: of Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

Melissa Monson (5704835)
Angelica Van Goor (3569357)
Christopher Ashwell (3569354)
Michael Persia (3569348)
Max Rothschild (3569351)
Carl Schmidt (3159513)
Susan Lamont (340168)

August 2018

Correlations between log2FC from RNA-seq and Biomark qPCR. Compares log2FC from RNA-seq and qPCR for...

Additional file 3: of Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

Melissa Monson (5704835)
Angelica Van Goor (3569357)
Christopher Ashwell (3569354)
Michael Persia (3569348)
Max Rothschild (3569351)
Carl Schmidt (3159513)
Susan Lamont (340168)

August 2018

Significant differential expression in each comparison between treatments or chicken lines. Contains...

Additional file 8: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S6. The correlation coefficient between receptor genes expression and ligand genes expression ...

Additional file 4: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S2. The gene expression level of the two groups. Sheet 1 showed the top 10 highest expression ...

Additional file 1: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S1. Characteristics of the reads from bursa of Fabricius libraries obtained from 2 groups. 1Mu...

Additional file 7: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S5. The KEGG enrichments of the differentially expressed genes of the C_B group and B_B group....

Additional file 3: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Figure S2. Venn diagram of global genes expressed in two groups. Red indicates the genes specific ex...

Additional file 6: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S4. The GO enrichment of SDEGs of the C_B group and B_B group. Sheet 1 showed the top 30 most ...

Additional file 5: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S3. The DEGs in the C_B group compared with the B_B group. Sheet 1 showed the SDEGs, sheet 2 s...

Additional file 9: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S7. Protein-protein interaction network for all SDEGs. Sheet 1 showed the interactions with a ...

Additional file 13: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S9. Effects of CORT treatment on immune related indexes of chickens. Data are shown as the mea...

Additional file 11: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Figure S4. 19 modules of the protein-protein interaction network with node > 3 and a MCODE score > 3...

Additional file 12: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang (356457)
Yanting Zhou (4039313)
Guirong Sun (3571250)
Kui Li (48173)
Zhuanjian Li (108072)
Aru Su (6085199)
Xiaojun Liu (58952)
Guoxi Li (63063)
Ruirui Jiang (5090348)
Ruili Han (4408216)
Yadong Tian (3580121)
Xiangtao Kang (3580112)
Fengbin Yan (6085202)

December 2018

Table S8. Effects of CORT treatment on the serum biochemical indexes of chickens. Data are shown as ...

Additional file 8: of Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

Melissa Monson (5704835)
Angelica Van Goor (3569357)
Christopher Ashwell (3569354)
Michael Persia (3569348)
Max Rothschild (3569351)
Carl Schmidt (3159513)
Susan Lamont (340168)

August 2018

Primers for qPCR validation of differential expression using the Biomark HD system. (DOCX 18 kb

Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Yanhua Zhang
Yanting Zhou
Guirong Sun
Kui Li
Zhuanjian Li
Aru Su
Xiaojun Liu
Guoxi Li
Ruirui Jiang
Ruili Han
Yadong Tian
Xiangtao Kang
Fengbin Yan

December 2018

Abstract Background The molecular mechanisms underlying stress-influenced immune function of chicken...

Additional file 4: of Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

Melissa Monson (5704835)
Angelica Van Goor (3569357)
Christopher Ashwell (3569354)
Michael Persia (3569348)
Max Rothschild (3569351)
Carl Schmidt (3159513)
Susan Lamont (340168)

August 2018

Correlations between log2FC from RNA-seq and Biomark qPCR. Compares log2FC from RNA-seq and qPCR for...

Additional file 3: of Immunomodulatory effects of heat stress and lipopolysaccharide on the bursal transcriptome in two distinct chicken lines

Melissa Monson (5704835)
Angelica Van Goor (3569357)
Christopher Ashwell (3569354)
Michael Persia (3569348)
Max Rothschild (3569351)
Carl Schmidt (3159513)
Susan Lamont (340168)

August 2018

Significant differential expression in each comparison between treatments or chicken lines. Contains...

Additional file 14: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Abstract

Extracted data

Additional file 14: of Transcriptome profile in bursa of Fabricius reveals potential mode for stress-influenced immune function in chicken stress model

Abstract

Extracted data

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