The relative frequencies of the CDR3 amino acid lengths of the VH (A), Vκ (B) and Vλ (C) genes are shown. Data are from four MID samples (N = 5675 for VH, 9360 for Vκ and 1230 for Vλ). CDR3s are defined according to IMGT unique numbering.</p
<p>Mean CDR3 lengths (amino acid residues) were calculated for IGH associated with each of the IgG a...
(A) CDRH3 length distributions of generic and significantly overshared TCR sequences. Significantly ...
<p>Male 1 (M1), Male 2 (M2) and Female 1 (F1).</p>*<p>Unseparated, memory and naïve samples 1 and 2 ...
<p>Percentages of BcR sequences of different lengths. <b>A</b>) Length distribution of heavy chain (...
<p>Positional amino acid frequencies in CDR-H3s of the same length. Length n = 15 was the approximat...
<p>(b) Frequency analysis for the IG genes and the length of the CDR3 of the heavy and light chain o...
<p>(A) The frequencies of charged amino acids encoded by the identified pentameric V<sub>H</sub> rep...
<p>The lengths of CDR3H of all sequences analyzed was divided into three groups. These groups were i...
<p>(A) 33B2 and 33C6 VH CDR amino acid sequences. (B) 33B2 and 33C6 VL CDR amino acid sequences.</p
(A) CDRH3 length distribution averaged over individuals within each cohort of B cell receptors. A co...
The third complementarity determining region (CDR3) of the immunoglobin (Ig) kappa (к) chain is know...
International audienceB cells are subjected to selection at multiple checkpoints during their develo...
<p>The group median for CDR1/2 in each of the 5 most frequently expressed V<sub>H</sub>3 genes (V<su...
<p><b>A</b>) Germline sequences of D<sub>H</sub> genes and translation in reading frames (RF) 1–3. D...
<p>B-cell antigen receptor (BCR) or antibody diversity arises from somatic recombination of immunogl...
<p>Mean CDR3 lengths (amino acid residues) were calculated for IGH associated with each of the IgG a...
(A) CDRH3 length distributions of generic and significantly overshared TCR sequences. Significantly ...
<p>Male 1 (M1), Male 2 (M2) and Female 1 (F1).</p>*<p>Unseparated, memory and naïve samples 1 and 2 ...
<p>Percentages of BcR sequences of different lengths. <b>A</b>) Length distribution of heavy chain (...
<p>Positional amino acid frequencies in CDR-H3s of the same length. Length n = 15 was the approximat...
<p>(b) Frequency analysis for the IG genes and the length of the CDR3 of the heavy and light chain o...
<p>(A) The frequencies of charged amino acids encoded by the identified pentameric V<sub>H</sub> rep...
<p>The lengths of CDR3H of all sequences analyzed was divided into three groups. These groups were i...
<p>(A) 33B2 and 33C6 VH CDR amino acid sequences. (B) 33B2 and 33C6 VL CDR amino acid sequences.</p
(A) CDRH3 length distribution averaged over individuals within each cohort of B cell receptors. A co...
The third complementarity determining region (CDR3) of the immunoglobin (Ig) kappa (к) chain is know...
International audienceB cells are subjected to selection at multiple checkpoints during their develo...
<p>The group median for CDR1/2 in each of the 5 most frequently expressed V<sub>H</sub>3 genes (V<su...
<p><b>A</b>) Germline sequences of D<sub>H</sub> genes and translation in reading frames (RF) 1–3. D...
<p>B-cell antigen receptor (BCR) or antibody diversity arises from somatic recombination of immunogl...
<p>Mean CDR3 lengths (amino acid residues) were calculated for IGH associated with each of the IgG a...
(A) CDRH3 length distributions of generic and significantly overshared TCR sequences. Significantly ...
<p>Male 1 (M1), Male 2 (M2) and Female 1 (F1).</p>*<p>Unseparated, memory and naïve samples 1 and 2 ...
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