Distribution of physicians’ estimates: Threshold for Unacceptable Risk of Non-Adherence for 70 drug-indication groups.

Each horizontal bar represents the distribution (in percentage) of physicians’ estimates for a given drug-indication group. TURN* corresponds to the frequency of missing doses above which 75% of physicians’ estimates were located (vertical dashed line). n* corresponds to the number of physicians’ assessments for each drug-indication group. For sake of clarity, we plotted 70 drug-indication groups corresponding to 90% of total prescription volume of the medications assessed in the study. All the 112 drug-indication groups are plotted in S2 Fig. Abbreviations: ACE: angiotensin-converting enzyme, ARBs: angiotensin receptor blockers, CCBs: calcium channel blockers; COPD: Chronic Obstructive Pulmonary Disease; GORD: gastro-oesophageal reflux diseases; HBP: high blood pressure; NSAIDs: non-steroidal anti-inflammatory drugs, MI: myocardial infarction.