Landmark analysis for the risks of CD/NFMI and MACEs.

The risk of CD and NFMI was higher in the groups with low obesity indexes (Q1 and Q2 of both BMI and WC) until 1 year of observation; however, it was not different among the groups stratified by either BMI or WC after 1 year of observation. BMI did not influence the risk of MACEs throughout the observation period. In contrast, the risk of MACEs was significantly higher in the Q1WC group than in the Q3WC group throughout the observation period (11.5% vs. 5.3%, p = 0.005). The risk of MACEs was not different between the Q3WC and Q4WC groups until 1 year of observation (5.3% vs. 7.1%, p = 0.332); however, it was higher in the Q4WC group after 1 year of observation (13.4% vs. 25.5%, p = 0.004). CD, cardiac death; NFMI, nonfatal myocardial infarction; MACE, major adverse cardiac event; BMI body mass index; and WC, waist circumference.