Table S1. Changes in chemokine expression after 12 h of light exposure. A 40-chemokine array was used to screen for cytokine expression in degenerating Arr1−/− retinas after 12 h of light exposure. Very few cytokines showed any appreciable change compared to dark-reared WT controls. The most dramatic was CCL2, which showed a 5.3-fold increase. Relative expression levels were calculated as light-exposure divided by dark reared for each group, then averaged across runs. A value of 1 indicates no change; shades of red are greater than 1.5, and shades of blue are less than 0.6. (DOCX 15 kb
<p>(A–C) The protein expressions of IL-1β and TNF-α in the retina began to increase at 6 hours after...
Figure S1. CD45hi/CD11b+/CD11c+ monocyte-like cells infiltrate early in D2 glaucoma. At ~â9 mo the...
Figure S5. KEGG analysis of enriched gene sets in ONH Monocytes Group 1. Scatter plots of genes by f...
Figure S1. Monocyte infiltration occurs through retinal vasculature and the optic nerve head. (A) Lo...
Figure S2. CCL2-neutralizing antibody remains in the eye for at least 12 h. A single injection of CC...
Figure S2. Retinal C3d protein levels in wild-type (WT) dim-reared controls and after 7 days of phot...
Additional file 1: Table S1: List of primary antibodies used in the study. figure S1: Estimation of ...
Early microglial activation after exposure to bright white light. Representative photomicrographs sh...
Summary of the distribution of microglia in the retinal layers. Microglia are distributed in diverse...
Figure S1. Characterisation of dim-reared C57BL/6 J wild-type (WT) and C1qa−/− mouse retinas. A-C: T...
qRT-PCR retinal gene expression results during development in normal, xlpra2, rcd1, and erd. Statist...
Figure S2. IL6/IL6Rα expression before and after acute retinal detachment. (A) Multiple cytokines ar...
Purpose: Microglial cells, which are activated and recruited by chemokines, have been shown to play ...
Figure S1. Celastrol protected retinas from light-induced degeneration in BALB/c mice. Figure S2. Ce...
Induction of Rhodopsin::GFP reporter by OC1-EnR and L-Maf. Retinas were electroporated with UbiC::Td...
<p>(A–C) The protein expressions of IL-1β and TNF-α in the retina began to increase at 6 hours after...
Figure S1. CD45hi/CD11b+/CD11c+ monocyte-like cells infiltrate early in D2 glaucoma. At ~â9 mo the...
Figure S5. KEGG analysis of enriched gene sets in ONH Monocytes Group 1. Scatter plots of genes by f...
Figure S1. Monocyte infiltration occurs through retinal vasculature and the optic nerve head. (A) Lo...
Figure S2. CCL2-neutralizing antibody remains in the eye for at least 12 h. A single injection of CC...
Figure S2. Retinal C3d protein levels in wild-type (WT) dim-reared controls and after 7 days of phot...
Additional file 1: Table S1: List of primary antibodies used in the study. figure S1: Estimation of ...
Early microglial activation after exposure to bright white light. Representative photomicrographs sh...
Summary of the distribution of microglia in the retinal layers. Microglia are distributed in diverse...
Figure S1. Characterisation of dim-reared C57BL/6 J wild-type (WT) and C1qa−/− mouse retinas. A-C: T...
qRT-PCR retinal gene expression results during development in normal, xlpra2, rcd1, and erd. Statist...
Figure S2. IL6/IL6Rα expression before and after acute retinal detachment. (A) Multiple cytokines ar...
Purpose: Microglial cells, which are activated and recruited by chemokines, have been shown to play ...
Figure S1. Celastrol protected retinas from light-induced degeneration in BALB/c mice. Figure S2. Ce...
Induction of Rhodopsin::GFP reporter by OC1-EnR and L-Maf. Retinas were electroporated with UbiC::Td...
<p>(A–C) The protein expressions of IL-1β and TNF-α in the retina began to increase at 6 hours after...
Figure S1. CD45hi/CD11b+/CD11c+ monocyte-like cells infiltrate early in D2 glaucoma. At ~â9 mo the...
Figure S5. KEGG analysis of enriched gene sets in ONH Monocytes Group 1. Scatter plots of genes by f...