A Mononuclear Nonheme Iron(IV)–Amido Complex Relevant for the Compound II Chemistry of Cytochrome P450

A mononuclear nonheme iron­(IV)–amido complex bearing a tetraamido macrocyclic ligand, [(TAML)­FeIV(NHTs)]− (1), was synthesized via a hydrogen atom (H atom) abstraction reaction of an iron­(V)–imido complex, [(TAML)­FeV(NTs)]− (2), and fully characterized using various spectroscopies. We then investigated (1) the pKa of 1, (2) the reaction of 1 with a carbon-centered radical, and (3) the H atom abstraction reaction of 1. To the best of our knowledge, the present study reports for the first time the synthesis and chemical properties/reactions of a high-valent iron­(IV)–amido complex