Figure S3. Unremarkable spinal cord pathology in aged MATR3WT and MATR3F115C mice. MATR3 immunohistochemistry of spinal cord at ~ 10 months of age from a NT, b MATR3WT from lead line 1563, and c MATR3F115C from lead line 1576. Qualitatively, there appeared to be no difference in Iba-1 immunohistochemistry between d NT, e MATR3WT, and f MATR3F115C, or in GFAP immunohistochemistry of g NT, h MATR3WT, and i MATR3F115C spinal cords. Scale bar measures 100 μm. (TIF 6303 kb
Figure S3. Effect size and distribution of eQTLs for PAK1. Jitter plots with overlaid violin plots s...
Class III mice. These figures represent the counterparts of Fig. 6. stained with MC1, CP27, RZ3 and ...
Figure S1. ΔKlotho mice display signs of sarcopenia. (A) Immunofluorescence of cross-sections of TA ...
Figure S2. MATR3 is not robustly elevated in the spinal cords of MATR3WT and MATR3F115C mice. a Nort...
Figure S1. Muscle immunobloting and pathology show striking differences between MATR3F115C mice from...
Table S2. Average body weights for lead MATR3WT and MATR3F115C lines. MATR3WT mice (lead line 1563) ...
Table S1. Animals used in the study. *Indicates genotype has been confirmed by sequencing. § indicat...
Figure S8. Primary pathology burden in the M83 transgenic mouse spinal cord relative to M83/G85R-SOD...
Figure S3. Primary pathology burden in the JNPL3 spinal cord relative to those crossed to G85R-SOD1:...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Figure S4. Behavioral Tests of Motor Phenotypes on Q394X Mice, related to Fig. 4. (A) Body weight of...
Progression of astrogliosis in control and PLP-α-syn mice was assessed by meaning GFAP OD. Although ...
Figure S5. Localization of phosphotau immunoreactivity versus G85R-SOD1:YFP pathology in bigenic JNP...
Figure S6. Upregulation of inflammatory cues in GCV-NestinTK mice. Real-time PCR analysis of pro-inf...
Figure S5. macrophages/macrophages activation affects both GCV-WT and GCV-NestinTK mice. (A) Histolo...
Figure S3. Effect size and distribution of eQTLs for PAK1. Jitter plots with overlaid violin plots s...
Class III mice. These figures represent the counterparts of Fig. 6. stained with MC1, CP27, RZ3 and ...
Figure S1. ΔKlotho mice display signs of sarcopenia. (A) Immunofluorescence of cross-sections of TA ...
Figure S2. MATR3 is not robustly elevated in the spinal cords of MATR3WT and MATR3F115C mice. a Nort...
Figure S1. Muscle immunobloting and pathology show striking differences between MATR3F115C mice from...
Table S2. Average body weights for lead MATR3WT and MATR3F115C lines. MATR3WT mice (lead line 1563) ...
Table S1. Animals used in the study. *Indicates genotype has been confirmed by sequencing. § indicat...
Figure S8. Primary pathology burden in the M83 transgenic mouse spinal cord relative to M83/G85R-SOD...
Figure S3. Primary pathology burden in the JNPL3 spinal cord relative to those crossed to G85R-SOD1:...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Figure S4. Behavioral Tests of Motor Phenotypes on Q394X Mice, related to Fig. 4. (A) Body weight of...
Progression of astrogliosis in control and PLP-α-syn mice was assessed by meaning GFAP OD. Although ...
Figure S5. Localization of phosphotau immunoreactivity versus G85R-SOD1:YFP pathology in bigenic JNP...
Figure S6. Upregulation of inflammatory cues in GCV-NestinTK mice. Real-time PCR analysis of pro-inf...
Figure S5. macrophages/macrophages activation affects both GCV-WT and GCV-NestinTK mice. (A) Histolo...
Figure S3. Effect size and distribution of eQTLs for PAK1. Jitter plots with overlaid violin plots s...
Class III mice. These figures represent the counterparts of Fig. 6. stained with MC1, CP27, RZ3 and ...
Figure S1. ΔKlotho mice display signs of sarcopenia. (A) Immunofluorescence of cross-sections of TA ...