(A) Quantification of septal collagen density and (B) photomicrographs of myocardial tissue stained with picrosirius red in rats, 4 weeks after sham-operation (Sham) or acute myocardial ischemia-reperfusion (IR), with no (NL), mild (ML) or large (LL) cardiac lesions. (C) Quantified values of MMP-2 activity and (D) its respective gelatin zymogram. Values are means ± SEM, * vs. Sham, P<0.05.</p
Background—Matrix metalloproteinase-2 (MMP-2) contributes to cardiac dysfunction resulting from isch...
<p>(B) Bar diagram showing percentage of fibrosis in saline treated and fC-MSC treated hearts. Value...
<p>At 21 days following infarction, fibrosis was measured by staining for collagen using picrosirius...
(A) Myocardial tissue concentrations of O2- and H2O2 and (B) TNF-α mRNA expression in rats 4 weeks a...
<p>(<b>A</b>) Myocardial collagen content measured by quantitative analysis of tissue hydroxyproline...
<p>A representative image of gelatin zymography (<b>A</b>), and quantitative analyses of MMP-2 (<b>B...
<p>A. Representative images showing the effects of RSE on histological changes in the heart after I/...
<p>Representative pictures of Sirus Red/Fast Green Collage staining to visualize fibrosis in rat hea...
Matrixmetalloproteinases (MMP) 2 and 9 as well as tissue inhibitor of metalloproteinases (TIMP) 1 we...
(A) Basal recordings of maximal increasing rate of left ventricular pressure (+dP/dt_max) and (B) Ch...
<p>Bottom panel (C and D) shows representative photomicrographs of Sirius red-stained ventricular ti...
<p>Bar graphs showing the extent of perivascular and interstitial myocardial fibrosis. * p<0.05 vs c...
Rats cardiac tissue was stained with Masson’s trichrome stain to visualize cardiomyocytes in red and...
<p>Note increased myocardial fibrous tissue content (depicted in red) in untreated SNX at 12 weeks (...
<p>Representative micrographs were obtained from each group. The morphological location (A) and the ...
Background—Matrix metalloproteinase-2 (MMP-2) contributes to cardiac dysfunction resulting from isch...
<p>(B) Bar diagram showing percentage of fibrosis in saline treated and fC-MSC treated hearts. Value...
<p>At 21 days following infarction, fibrosis was measured by staining for collagen using picrosirius...
(A) Myocardial tissue concentrations of O2- and H2O2 and (B) TNF-α mRNA expression in rats 4 weeks a...
<p>(<b>A</b>) Myocardial collagen content measured by quantitative analysis of tissue hydroxyproline...
<p>A representative image of gelatin zymography (<b>A</b>), and quantitative analyses of MMP-2 (<b>B...
<p>A. Representative images showing the effects of RSE on histological changes in the heart after I/...
<p>Representative pictures of Sirus Red/Fast Green Collage staining to visualize fibrosis in rat hea...
Matrixmetalloproteinases (MMP) 2 and 9 as well as tissue inhibitor of metalloproteinases (TIMP) 1 we...
(A) Basal recordings of maximal increasing rate of left ventricular pressure (+dP/dt_max) and (B) Ch...
<p>Bottom panel (C and D) shows representative photomicrographs of Sirius red-stained ventricular ti...
<p>Bar graphs showing the extent of perivascular and interstitial myocardial fibrosis. * p<0.05 vs c...
Rats cardiac tissue was stained with Masson’s trichrome stain to visualize cardiomyocytes in red and...
<p>Note increased myocardial fibrous tissue content (depicted in red) in untreated SNX at 12 weeks (...
<p>Representative micrographs were obtained from each group. The morphological location (A) and the ...
Background—Matrix metalloproteinase-2 (MMP-2) contributes to cardiac dysfunction resulting from isch...
<p>(B) Bar diagram showing percentage of fibrosis in saline treated and fC-MSC treated hearts. Value...
<p>At 21 days following infarction, fibrosis was measured by staining for collagen using picrosirius...