Collagen deposition in tissue sections.

(A) Representative photomicrographs of Gomori’s trichrome-stained tissue sections at treatment day 14 and 28. White arrows denote diffuse areas of collagen deposition and yellow arrows denote thicker collagen fibers. Inset indicates area used for quantification. Scale bar = 300 μm, inset scale bar = 75 μm. (B) Fold change collagen relative to model-matched, vehicle-treated control. Data represent the mean of the fold change + SEM at each timepoint (n = 2).