Basal levels of C activity markers were determined without activation. (A) The levels of sC5b-9 were measured in NC (white bars): n = 14; CLL with normal C5 (grey bars): n = 20; CLL with abnormal C5 (black bars): n = 16. *p = 0.043 vs. NC. Values are given as mean with SEM. **pB) Basal C activity was also assessed by the levels of C5a in NC: n = 7; CLL with normal C5: n = 14; CLL with abnormal C5: n = 15. ##p = 0.001 vs. NC and #p = 0.012 vs. CLL with normal C5. Values are given as mean with SEM. (C) The correlation between the basal levels of C5a and sC5b-9 was analyzed in all subjects. NC (white circles): n = 7; CLL with normal C5 (grey circles): n = 15; CLL with abnormal C5 (black circles): n = 15.</p
Background Complement activation plays an important pathogenic role in numerous diseases. The ratio...
<p>Sera were collected on indicated days from mice described in <a href="http://www.plosone.org/arti...
Background: The complement system is an essential component of our innate defense and plays a vital ...
C was activated in-vitro via the CP by aggregated IgG (A) or via the AP by Zymosan (B) and levels of...
C5-deficient serum was supplemented with 33% serum from CLL or NC or with purified C5 (positive cont...
Subjects’ sera were supplemented with purified C5 (commercial) to physiological concentration. C act...
C activation was inhibited in subjects’ sera by EDTA. Sera were then supplemented with classical C5-...
The potential identity of the abnormal C5 as C5b was assessed by Western analysis using anti-C5 and ...
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. The thera...
Complement C5 component was followed in plasma under non-reducing conditions, by Western analysis us...
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. The thera...
The purpose of this study is to clarify the relationship between serum complement hemolytic activity...
<p>Mean complement activities and concentrations in chronic central serous chorioretinopathy (CSC) p...
Complement systemaberrations have been identified as pathophysiological mechanisms in a number of di...
<p>(A) C5a concentrations in CF sols positively correlate with increasing age, r = 0.53, <i>p</i> = ...
Background Complement activation plays an important pathogenic role in numerous diseases. The ratio...
<p>Sera were collected on indicated days from mice described in <a href="http://www.plosone.org/arti...
Background: The complement system is an essential component of our innate defense and plays a vital ...
C was activated in-vitro via the CP by aggregated IgG (A) or via the AP by Zymosan (B) and levels of...
C5-deficient serum was supplemented with 33% serum from CLL or NC or with purified C5 (positive cont...
Subjects’ sera were supplemented with purified C5 (commercial) to physiological concentration. C act...
C activation was inhibited in subjects’ sera by EDTA. Sera were then supplemented with classical C5-...
The potential identity of the abnormal C5 as C5b was assessed by Western analysis using anti-C5 and ...
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. The thera...
Complement C5 component was followed in plasma under non-reducing conditions, by Western analysis us...
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. The thera...
The purpose of this study is to clarify the relationship between serum complement hemolytic activity...
<p>Mean complement activities and concentrations in chronic central serous chorioretinopathy (CSC) p...
Complement systemaberrations have been identified as pathophysiological mechanisms in a number of di...
<p>(A) C5a concentrations in CF sols positively correlate with increasing age, r = 0.53, <i>p</i> = ...
Background Complement activation plays an important pathogenic role in numerous diseases. The ratio...
<p>Sera were collected on indicated days from mice described in <a href="http://www.plosone.org/arti...
Background: The complement system is an essential component of our innate defense and plays a vital ...