MOESM5 of A novel signature derived from immunoregulatory and hypoxia genes predicts prognosis in liver and five other cancers

Additional file 5. Multidimensional scaling analysis of the 45-gene signature and disease-free survival analysis. (A) Ordination plots of multidimensional scaling analysis of the signature in HCC cohorts using Euclidean distances revealed significant separation of tumor (T) and non-tumor (NT) samples represented in a 2-dimensional space. Axes represent the first and second dimension. The distinction of T and NT was confirmed by PERMANOVA tests. (B) Kaplan-Meier plot of disease-free survival in HCC patients from the GSE14520 cohort stratified into low- and high-risk groups using the 45-gene signature. Disease-free survival is defined as the time from surgery to recurrence, death from any cause or distant metastasis. P-values are calculated from the log-rank test