Additional file 1: of Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

Additional file 1: of A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer

Lynne Kerr (3452774)
Matthew Rewhorn (3452768)
Mark Longmuir (3452771)
Sioban Fraser (3452780)
Shaun Walsh (3452765)
Nicola Andrew (3452777)
Hing Leung (425854)

July 2016

Tables showing patient details according to the genetic background. (DOCX 184 kb

Additional file 2: Table S1. of High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients

Muhammad Rashid (2836631)
Noor Muhammad (820180)
Seerat Bajwa (3428105)
Saima Faisal (3428111)
Muhammad Tahseen (3428102)
Justo Bermejo (3428108)
Asim Amin (3428114)
Asif Loya (651095)
Ute Hamann (89879)

August 2016

Deleterious BRCA1/2 germline mutations in Pakistani patients with TNBC. (DOCX 24Â kb

Additional file 3: of Identification of novel common breast cancer risk variants at the 6q25 locusÂ among Latinas

Joshua Hoffman (3542453)
Laura Fejerman (172870)
Donglei Hu (156485)
Scott Huntsman (172836)
Min Li (12799)
Esther John (413149)
Gabriela Torres-Mejia (3088776)
Larry Kushi (6206879)
Yuan Ding (617135)
Jeffrey Weitzel (269835)
Susan Neuhausen (3405332)
Paul Lott (6206885)
Magdalena Echeverry (6206891)
Luis Carvajal-Carmona (364407)
Esteban Burchard (1262)
Celeste Eng (179050)
Jirong Long (181371)
Wei Zheng (25452)
Olufunmilayo Olopade (3405344)
Dezheng Huo (151859)
Christopher Haiman (120857)
Elad Ziv (1263)

January 2019

Table S6. Results of the top candidate SNPs analyzed using RegulomeDB (XLSX 12 kb

Additional file 2: of Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

J. Fernández-Lopez (6197366)
S. Romero-Córdoba (6197369)
R. Rebollar-Vega (6197375)
L. Alfaro-Ruiz (6197381)
S. Jiménez-Morales (6197384)
F. Beltrán-Anaya (6197390)
R. Arellano-Llamas (6197396)
A. Cedro-Tanda (6197399)
M. Rios-Romero (6197402)
M. Ramirez-Florencio (6197405)
V. Bautista-Piña (6197408)
C. Dominguez-Reyes (6197411)
F. Villegas-Carlos (6197414)
A. Tenorio-Torres (6197417)
A. Hidalgo-Miranda (6197420)

January 2019

Table S2. All variants detected in BRCA1 in the 3842 SIGMA samples, together with their annotation. ...

Additional file 3: of Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

J. Fernández-Lopez (6197366)
S. Romero-Córdoba (6197369)
R. Rebollar-Vega (6197375)
L. Alfaro-Ruiz (6197381)
S. Jiménez-Morales (6197384)
F. Beltrán-Anaya (6197390)
R. Arellano-Llamas (6197396)
A. Cedro-Tanda (6197399)
M. Rios-Romero (6197402)
M. Ramirez-Florencio (6197405)
V. Bautista-Piña (6197408)
C. Dominguez-Reyes (6197411)
F. Villegas-Carlos (6197414)
A. Tenorio-Torres (6197417)
A. Hidalgo-Miranda (6197420)

January 2019

Table S3. All variants detected in BRCA2 in the 3842 SIGMA samples, together with their annotation. ...

Additional file 3: of Hereditary breast and ovarian cancer in Andalusian families: a genetic population study

Bella Pajares (535703)
Javier Porta (5353961)
Jose Porta (5353967)
Cristina Sousa (5353982)
Ignacio Moreno (183571)
Daniel Porta (5353976)
Gema DurĂĄn (5354003)
Tamara Vega (5353970)
Inmaculada Ortiz (1707538)
Carolina Muriel (5353979)
Emilio Alba (535706)
Antonia MĂĄrquez (5354006)

June 2018

Table S3. Breast cancer tumour phenotypes according to BRCA1 and BRCA2 mutated cases. (DOC 14 kb

Additional file 1: of Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Shahi (6557546)
Sylvia De Brakeleer (6557549)
Ben Caljon (657226)
Ingrid Pauwels (6557552)
Maryse Bonduelle (6557555)
Sofie Joris (6557558)
Christel Fontaine (6557561)
Marian Vanhoeij (6557564)
Sonia Van Dooren (6557567)
Erik Teugels (88625)
Jacques De GrĂ¨ve (5881196)

April 2019

Breast cancer (BC) patients considered for the study, their age at diagnosis and the number of affec...

Additional file 2: of Identification of novel common breast cancer risk variants at the 6q25 locusÂ among Latinas

Joshua Hoffman (3542453)
Laura Fejerman (172870)
Donglei Hu (156485)
Scott Huntsman (172836)
Min Li (12799)
Esther John (413149)
Gabriela Torres-Mejia (3088776)
Larry Kushi (6206879)
Yuan Ding (617135)
Jeffrey Weitzel (269835)
Susan Neuhausen (3405332)
Paul Lott (6206885)
Magdalena Echeverry (6206891)
Luis Carvajal-Carmona (364407)
Esteban Burchard (1262)
Celeste Eng (179050)
Jirong Long (181371)
Wei Zheng (25452)
Olufunmilayo Olopade (3405344)
Dezheng Huo (151859)
Christopher Haiman (120857)
Elad Ziv (1263)

January 2019

Tables S2-S5. Supplementary tables including linkage disequilibrium between top SNPs and previously ...

Additional file 6: of Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Shahi (6557546)
Sylvia De Brakeleer (6557549)
Ben Caljon (657226)
Ingrid Pauwels (6557552)
Maryse Bonduelle (6557555)
Sofie Joris (6557558)
Christel Fontaine (6557561)
Marian Vanhoeij (6557564)
Sonia Van Dooren (6557567)
Erik Teugels (88625)
Jacques De GrĂ¨ve (5881196)

April 2019

BC patients vs. controls variant types enrichment in exome- and CAGP-wide. (XLSX 10 kb

Additional file 10: of Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Shahi (6557546)
Sylvia De Brakeleer (6557549)
Ben Caljon (657226)
Ingrid Pauwels (6557552)
Maryse Bonduelle (6557555)
Sofie Joris (6557558)
Christel Fontaine (6557561)
Marian Vanhoeij (6557564)
Sonia Van Dooren (6557567)
Erik Teugels (88625)
Jacques De GrĂ¨ve (5881196)

April 2019

List with PDAVs detected in 54âBC patients located in genes linked to (hereditary) cancer and/or h...

Additional file 5: of Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Shahi (6557546)
Sylvia De Brakeleer (6557549)
Ben Caljon (657226)
Ingrid Pauwels (6557552)
Maryse Bonduelle (6557555)
Sofie Joris (6557558)
Christel Fontaine (6557561)
Marian Vanhoeij (6557564)
Sonia Van Dooren (6557567)
Erik Teugels (88625)
Jacques De GrĂ¨ve (5881196)

April 2019

Types and number of variants detected (exome- and CAGP-wide) before and after variant filtration in ...

Additional file 5: of Gene-expression patterns in peripheral blood classify familial breast cancer susceptibility

Stephen Piccolo (3566870)
Irene Andrulis (547071)
Adam Cohen (767228)
Thomas Conner (3566873)
Philip Moos (3566867)
Avrum Spira (5655)
Saundra Buys (196721)
W. Johnson (3547424)
Andrea Bild (3566876)

November 2015

Cancer, family-history, and BRCA1/2 status for all patients. This file indicates cancer, family hist...

Additional file 1: of Prevalence of breast and ovarian cancer subtypes in Hispanic populations from Puerto Rico

Ariel Rodriguez-Velazquez (6016826)
Rosa Velez (6016829)
Jean Lafontaine (6016832)
Claudia Colon-Echevarria (6016835)
Rocio Lamboy-Caraballo (6016838)
Ingrid Ramirez (6016841)
Adalberto Mendoza (6016844)
Patricia Casbas-Hernandez (6016847)
Guillermo Armaiz-Pena (6016850)

November 2018

Table S5. Manufacturer and clone information for antibodies used for IHC analyses. (DOCX 18 kb

Additional file 5: of Hereditary breast and ovarian cancer in Andalusian families: a genetic population study

Bella Pajares (535703)
Javier Porta (5353961)
Jose Porta (5353967)
Cristina Sousa (5353982)
Ignacio Moreno (183571)
Daniel Porta (5353976)
Gema DurĂĄn (5354003)
Tamara Vega (5353970)
Inmaculada Ortiz (1707538)
Carolina Muriel (5353979)
Emilio Alba (535706)
Antonia MĂĄrquez (5354006)

June 2018

Table S5. BRCA2 pathological germline mutations according to selection criteria and clinical charact...

Additional file 1: of Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil

Sabino, Ester Cerdeira
Cabral, Larissa Garcia
de Bock, Truuske
Maistro, Simone
de Gouvêa, Ana Carolina Ribeiro Chaves
Ribeiro, Roberto Marques
Teixeira, Natalia
Encinas, Giselly
Diz, Maria del Pilar Estevez
Gaburo Junior, Nelson
Carraro, Dirce Maria
Katayama, Maria Lucia Hirata
Niewiadonski, Vivian Dionisio Tavares
Folgueira, Maria Aparecida Azevedo Koike
Chammas, Roger
Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE)
Life Course Epidemiology (LCE)
Damage and Repair in Cancer Development and Cancer Treatment (DARE)

March 2017

Supplementary Methods. Table S1. Clinical and pathological characteristics, BRCA sequencing and MLPA...

Additional file 1: of A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer

Lynne Kerr (3452774)
Matthew Rewhorn (3452768)
Mark Longmuir (3452771)
Sioban Fraser (3452780)
Shaun Walsh (3452765)
Nicola Andrew (3452777)
Hing Leung (425854)

July 2016

Tables showing patient details according to the genetic background. (DOCX 184 kb

Additional file 2: Table S1. of High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients

Muhammad Rashid (2836631)
Noor Muhammad (820180)
Seerat Bajwa (3428105)
Saima Faisal (3428111)
Muhammad Tahseen (3428102)
Justo Bermejo (3428108)
Asim Amin (3428114)
Asif Loya (651095)
Ute Hamann (89879)

August 2016

Deleterious BRCA1/2 germline mutations in Pakistani patients with TNBC. (DOCX 24Â kb

Additional file 3: of Identification of novel common breast cancer risk variants at the 6q25 locusÂ among Latinas

Joshua Hoffman (3542453)
Laura Fejerman (172870)
Donglei Hu (156485)
Scott Huntsman (172836)
Min Li (12799)
Esther John (413149)
Gabriela Torres-Mejia (3088776)
Larry Kushi (6206879)
Yuan Ding (617135)
Jeffrey Weitzel (269835)
Susan Neuhausen (3405332)
Paul Lott (6206885)
Magdalena Echeverry (6206891)
Luis Carvajal-Carmona (364407)
Esteban Burchard (1262)
Celeste Eng (179050)
Jirong Long (181371)
Wei Zheng (25452)
Olufunmilayo Olopade (3405344)
Dezheng Huo (151859)
Christopher Haiman (120857)
Elad Ziv (1263)

January 2019

Table S6. Results of the top candidate SNPs analyzed using RegulomeDB (XLSX 12 kb

Additional file 2: of Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

J. Fernández-Lopez (6197366)
S. Romero-Córdoba (6197369)
R. Rebollar-Vega (6197375)
L. Alfaro-Ruiz (6197381)
S. Jiménez-Morales (6197384)
F. Beltrán-Anaya (6197390)
R. Arellano-Llamas (6197396)
A. Cedro-Tanda (6197399)
M. Rios-Romero (6197402)
M. Ramirez-Florencio (6197405)
V. Bautista-Piña (6197408)
C. Dominguez-Reyes (6197411)
F. Villegas-Carlos (6197414)
A. Tenorio-Torres (6197417)
A. Hidalgo-Miranda (6197420)

January 2019

Table S2. All variants detected in BRCA1 in the 3842 SIGMA samples, together with their annotation. ...

Additional file 3: of Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

J. Fernández-Lopez (6197366)
S. Romero-Córdoba (6197369)
R. Rebollar-Vega (6197375)
L. Alfaro-Ruiz (6197381)
S. Jiménez-Morales (6197384)
F. Beltrán-Anaya (6197390)
R. Arellano-Llamas (6197396)
A. Cedro-Tanda (6197399)
M. Rios-Romero (6197402)
M. Ramirez-Florencio (6197405)
V. Bautista-Piña (6197408)
C. Dominguez-Reyes (6197411)
F. Villegas-Carlos (6197414)
A. Tenorio-Torres (6197417)
A. Hidalgo-Miranda (6197420)

January 2019

Table S3. All variants detected in BRCA2 in the 3842 SIGMA samples, together with their annotation. ...

Additional file 3: of Hereditary breast and ovarian cancer in Andalusian families: a genetic population study

Bella Pajares (535703)
Javier Porta (5353961)
Jose Porta (5353967)
Cristina Sousa (5353982)
Ignacio Moreno (183571)
Daniel Porta (5353976)
Gema DurĂĄn (5354003)
Tamara Vega (5353970)
Inmaculada Ortiz (1707538)
Carolina Muriel (5353979)
Emilio Alba (535706)
Antonia MĂĄrquez (5354006)

June 2018

Table S3. Breast cancer tumour phenotypes according to BRCA1 and BRCA2 mutated cases. (DOC 14 kb

Additional file 1: of Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Shahi (6557546)
Sylvia De Brakeleer (6557549)
Ben Caljon (657226)
Ingrid Pauwels (6557552)
Maryse Bonduelle (6557555)
Sofie Joris (6557558)
Christel Fontaine (6557561)
Marian Vanhoeij (6557564)
Sonia Van Dooren (6557567)
Erik Teugels (88625)
Jacques De GrĂ¨ve (5881196)

April 2019

Breast cancer (BC) patients considered for the study, their age at diagnosis and the number of affec...

Additional file 2: of Identification of novel common breast cancer risk variants at the 6q25 locusÂ among Latinas

Joshua Hoffman (3542453)
Laura Fejerman (172870)
Donglei Hu (156485)
Scott Huntsman (172836)
Min Li (12799)
Esther John (413149)
Gabriela Torres-Mejia (3088776)
Larry Kushi (6206879)
Yuan Ding (617135)
Jeffrey Weitzel (269835)
Susan Neuhausen (3405332)
Paul Lott (6206885)
Magdalena Echeverry (6206891)
Luis Carvajal-Carmona (364407)
Esteban Burchard (1262)
Celeste Eng (179050)
Jirong Long (181371)
Wei Zheng (25452)
Olufunmilayo Olopade (3405344)
Dezheng Huo (151859)
Christopher Haiman (120857)
Elad Ziv (1263)

January 2019

Tables S2-S5. Supplementary tables including linkage disequilibrium between top SNPs and previously ...

Additional file 6: of Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Shahi (6557546)
Sylvia De Brakeleer (6557549)
Ben Caljon (657226)
Ingrid Pauwels (6557552)
Maryse Bonduelle (6557555)
Sofie Joris (6557558)
Christel Fontaine (6557561)
Marian Vanhoeij (6557564)
Sonia Van Dooren (6557567)
Erik Teugels (88625)
Jacques De GrĂ¨ve (5881196)

April 2019

BC patients vs. controls variant types enrichment in exome- and CAGP-wide. (XLSX 10 kb

Additional file 10: of Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Shahi (6557546)
Sylvia De Brakeleer (6557549)
Ben Caljon (657226)
Ingrid Pauwels (6557552)
Maryse Bonduelle (6557555)
Sofie Joris (6557558)
Christel Fontaine (6557561)
Marian Vanhoeij (6557564)
Sonia Van Dooren (6557567)
Erik Teugels (88625)
Jacques De GrĂ¨ve (5881196)

April 2019

List with PDAVs detected in 54âBC patients located in genes linked to (hereditary) cancer and/or h...

Additional file 5: of Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Shahi (6557546)
Sylvia De Brakeleer (6557549)
Ben Caljon (657226)
Ingrid Pauwels (6557552)
Maryse Bonduelle (6557555)
Sofie Joris (6557558)
Christel Fontaine (6557561)
Marian Vanhoeij (6557564)
Sonia Van Dooren (6557567)
Erik Teugels (88625)
Jacques De GrĂ¨ve (5881196)

April 2019

Types and number of variants detected (exome- and CAGP-wide) before and after variant filtration in ...

Additional file 5: of Gene-expression patterns in peripheral blood classify familial breast cancer susceptibility

Stephen Piccolo (3566870)
Irene Andrulis (547071)
Adam Cohen (767228)
Thomas Conner (3566873)
Philip Moos (3566867)
Avrum Spira (5655)
Saundra Buys (196721)
W. Johnson (3547424)
Andrea Bild (3566876)

November 2015

Cancer, family-history, and BRCA1/2 status for all patients. This file indicates cancer, family hist...

Additional file 1: of Prevalence of breast and ovarian cancer subtypes in Hispanic populations from Puerto Rico

Ariel Rodriguez-Velazquez (6016826)
Rosa Velez (6016829)
Jean Lafontaine (6016832)
Claudia Colon-Echevarria (6016835)
Rocio Lamboy-Caraballo (6016838)
Ingrid Ramirez (6016841)
Adalberto Mendoza (6016844)
Patricia Casbas-Hernandez (6016847)
Guillermo Armaiz-Pena (6016850)

November 2018

Table S5. Manufacturer and clone information for antibodies used for IHC analyses. (DOCX 18 kb

Additional file 5: of Hereditary breast and ovarian cancer in Andalusian families: a genetic population study

Bella Pajares (535703)
Javier Porta (5353961)
Jose Porta (5353967)
Cristina Sousa (5353982)
Ignacio Moreno (183571)
Daniel Porta (5353976)
Gema DurĂĄn (5354003)
Tamara Vega (5353970)
Inmaculada Ortiz (1707538)
Carolina Muriel (5353979)
Emilio Alba (535706)
Antonia MĂĄrquez (5354006)

June 2018

Table S5. BRCA2 pathological germline mutations according to selection criteria and clinical charact...

Additional file 1: of Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil

Sabino, Ester Cerdeira
Cabral, Larissa Garcia
de Bock, Truuske
Maistro, Simone
de Gouvêa, Ana Carolina Ribeiro Chaves
Ribeiro, Roberto Marques
Teixeira, Natalia
Encinas, Giselly
Diz, Maria del Pilar Estevez
Gaburo Junior, Nelson
Carraro, Dirce Maria
Katayama, Maria Lucia Hirata
Niewiadonski, Vivian Dionisio Tavares
Folgueira, Maria Aparecida Azevedo Koike
Chammas, Roger
Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE)
Life Course Epidemiology (LCE)
Damage and Repair in Cancer Development and Cancer Treatment (DARE)

March 2017

Supplementary Methods. Table S1. Clinical and pathological characteristics, BRCA sequencing and MLPA...

Additional file 1: of A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer

Lynne Kerr (3452774)
Matthew Rewhorn (3452768)
Mark Longmuir (3452771)
Sioban Fraser (3452780)
Shaun Walsh (3452765)
Nicola Andrew (3452777)
Hing Leung (425854)

July 2016

Tables showing patient details according to the genetic background. (DOCX 184 kb

Additional file 2: Table S1. of High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients

Muhammad Rashid (2836631)
Noor Muhammad (820180)
Seerat Bajwa (3428105)
Saima Faisal (3428111)
Muhammad Tahseen (3428102)
Justo Bermejo (3428108)
Asim Amin (3428114)
Asif Loya (651095)
Ute Hamann (89879)

August 2016

Deleterious BRCA1/2 germline mutations in Pakistani patients with TNBC. (DOCX 24Â kb

Additional file 3: of Identification of novel common breast cancer risk variants at the 6q25 locusÂ among Latinas

Joshua Hoffman (3542453)
Laura Fejerman (172870)
Donglei Hu (156485)
Scott Huntsman (172836)
Min Li (12799)
Esther John (413149)
Gabriela Torres-Mejia (3088776)
Larry Kushi (6206879)
Yuan Ding (617135)
Jeffrey Weitzel (269835)
Susan Neuhausen (3405332)
Paul Lott (6206885)
Magdalena Echeverry (6206891)
Luis Carvajal-Carmona (364407)
Esteban Burchard (1262)
Celeste Eng (179050)
Jirong Long (181371)
Wei Zheng (25452)
Olufunmilayo Olopade (3405344)
Dezheng Huo (151859)
Christopher Haiman (120857)
Elad Ziv (1263)

January 2019

Table S6. Results of the top candidate SNPs analyzed using RegulomeDB (XLSX 12 kb

Additional file 1: of Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

Abstract

Extracted data

Additional file 1: of Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

Abstract

Extracted data

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