Analysis of ROS in DD compared to NFF.
- Julia Krassovka (6199619)
- Annika Borgschulze (6199622)
- Benita Sahlender (6199625)
- Tim Lögters (37173)
- Joachim Windolf (37178)
- Vera Grotheer (6199628)
Publication date
January 2019
DOI Publisher
Public Library of Science (PLoS)Abstract
A ROS generation of irradiated (60 Joule/cm2) or resting NPF (n = 5) compared to DD fibroblasts (n = 5). Measurement after 0.5, 1, 2, 4, and 24 h with DHR123. Absolute ROS expression of fibroblasts increased after irradiation. Both irradiated and non-irradiated fibroblasts of DD always revealed the highest ROS expression compared to irradiated and non-irradiated NPF fibroblasts (Fig 4A). ROS expression rose over 24 h continuously. Nevertheless, the ROS expression of irradiated NPF fibroblasts was significantly enhanced after 24 h compared to irradiated NPF fibroblasts after 0.5, 1, and 2 h. The irradiated NPF fibroblasts showed a significant boost after 24 h compared to non-irradiated NPF fibroblasts.</p
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