Figure S2. MDA-MB-231 cells implanted into animals display metastatic burden in the lungs that is reduced by MDM2 or MDMX knockdown. Representative images of metastatic burden in the lungs in vector control group. A) Shows representative comparisons of lungs from animals with 231.mir30.vector, 231.shmdm2 or 231.shmdmx engrafted cells. Arrow points to metastases. H&E staining at 12.5X (upper panel) and 200X (lower panel) magnification. B) Shows a quantitation of the lung metastasis. (JPG 9785 kb
The murine xenograft model Schematic diagrams illustrate the use of 12 SCID mice associated with eac...
COX-2 inhibition and lung metastasis. a Lung metastases tend to be increased in PyMT/Cola1a tumors a...
Figure S1. Scheme of the experimental procedure (A). Body weight comparison between ovariectomized (...
Figure S1. MDA-MB-231 transplants have locally invasive growth. H&E staining of three representative...
Figure S4. siRNA-mediated MDM2 or MDMX silencing reduced MDA-MB-231 and MDA-MB-468 cell migration. (...
Figure S5. Variable Levels of MDM2 and MDMX in Different Breast Cancer Cell Lines. Cell lysates from...
Figure S1. Effect of host Sdc1 on metastatic efficiency of E0771 mouse mammary carcinoma cells. E077...
Figure S2. Characterization of 4T1 primary fat pad tumors. The 4T1 tumor cells (1 × 107 cells in 10 ...
Figure S3. Effect of host Sdc1 on later stages of E0771 carcinoma cell metastasis. E0771 tumor cells...
Additional file 2: Figure S2. DEX promotes tumour metastases in mice exposed to tumour excision. 1 ×...
a Comparison of individual tumor growth plots for 468-shCDH1-B and 468-shCDH1-D tumors to day of tum...
The murine xenograft model. Schematic diagrams illustrate the use of 12 SCID mice associated with ea...
Figure S4. Flow cytometric analysis of PDX tumor shows obASCs promote EMT and increase classically a...
Effect of SHP2 silencing on the tumorigenic potential of MDA-MB-468 cells. a Tumor growth rate as de...
Figure S4. Estrogen promotes lung metastasis of Brca1-deficient mammary tumors. (A, B) Metastatic p1...
The murine xenograft model Schematic diagrams illustrate the use of 12 SCID mice associated with eac...
COX-2 inhibition and lung metastasis. a Lung metastases tend to be increased in PyMT/Cola1a tumors a...
Figure S1. Scheme of the experimental procedure (A). Body weight comparison between ovariectomized (...
Figure S1. MDA-MB-231 transplants have locally invasive growth. H&E staining of three representative...
Figure S4. siRNA-mediated MDM2 or MDMX silencing reduced MDA-MB-231 and MDA-MB-468 cell migration. (...
Figure S5. Variable Levels of MDM2 and MDMX in Different Breast Cancer Cell Lines. Cell lysates from...
Figure S1. Effect of host Sdc1 on metastatic efficiency of E0771 mouse mammary carcinoma cells. E077...
Figure S2. Characterization of 4T1 primary fat pad tumors. The 4T1 tumor cells (1 × 107 cells in 10 ...
Figure S3. Effect of host Sdc1 on later stages of E0771 carcinoma cell metastasis. E0771 tumor cells...
Additional file 2: Figure S2. DEX promotes tumour metastases in mice exposed to tumour excision. 1 ×...
a Comparison of individual tumor growth plots for 468-shCDH1-B and 468-shCDH1-D tumors to day of tum...
The murine xenograft model. Schematic diagrams illustrate the use of 12 SCID mice associated with ea...
Figure S4. Flow cytometric analysis of PDX tumor shows obASCs promote EMT and increase classically a...
Effect of SHP2 silencing on the tumorigenic potential of MDA-MB-468 cells. a Tumor growth rate as de...
Figure S4. Estrogen promotes lung metastasis of Brca1-deficient mammary tumors. (A, B) Metastatic p1...
The murine xenograft model Schematic diagrams illustrate the use of 12 SCID mice associated with eac...
COX-2 inhibition and lung metastasis. a Lung metastases tend to be increased in PyMT/Cola1a tumors a...
Figure S1. Scheme of the experimental procedure (A). Body weight comparison between ovariectomized (...