Representative chromatograms of (A) blank of dried blood spot, (B) LLOQ (50 pg/mL), (C) medium quality control (900 pg/mL) and (D) the sample from a paediatric patient.</p
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilita...
© 2017 Elsevier B.V. Dexmedetomidine (DMET) is a sedative, analgesic and anxiolytic with minimum adv...
The collection of dried blood spots on filter paper offers a powerful tool in screening programs and...
Fragmentation patterns of dexmedetomidine (upper panel) and internal standard (lower panel). The pre...
Dexmedetomidine is an imidazole derivative, with high affinity for α2 adrenergic receptors, used for...
Dexmedetomidine is an imidazole derivative, with high affinity for α2 adrenergic receptors, used for...
Validation tests of the analytical method by LC-MS/MS for the quantification of dexmedetomidine in d...
Four samples were taken from each participant; the average of the determinations is shown in squares...
Development and validation of a selective and sensitive LCMS method for the determination of methotr...
Development and validation of a selective and sensitive LCMS method for the determination of methotr...
A high-performance liquid chromatography (LC-MS) method has been developed and validated for the det...
The collection of whole blood samples on paper, known as dried blood spot (DBS), dates back to the e...
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilita...
Objectives: Conduction of pharmacokinetic (PK) study in pediatric patients is challenging due to blo...
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilita...
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilita...
© 2017 Elsevier B.V. Dexmedetomidine (DMET) is a sedative, analgesic and anxiolytic with minimum adv...
The collection of dried blood spots on filter paper offers a powerful tool in screening programs and...
Fragmentation patterns of dexmedetomidine (upper panel) and internal standard (lower panel). The pre...
Dexmedetomidine is an imidazole derivative, with high affinity for α2 adrenergic receptors, used for...
Dexmedetomidine is an imidazole derivative, with high affinity for α2 adrenergic receptors, used for...
Validation tests of the analytical method by LC-MS/MS for the quantification of dexmedetomidine in d...
Four samples were taken from each participant; the average of the determinations is shown in squares...
Development and validation of a selective and sensitive LCMS method for the determination of methotr...
Development and validation of a selective and sensitive LCMS method for the determination of methotr...
A high-performance liquid chromatography (LC-MS) method has been developed and validated for the det...
The collection of whole blood samples on paper, known as dried blood spot (DBS), dates back to the e...
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilita...
Objectives: Conduction of pharmacokinetic (PK) study in pediatric patients is challenging due to blo...
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilita...
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilita...
© 2017 Elsevier B.V. Dexmedetomidine (DMET) is a sedative, analgesic and anxiolytic with minimum adv...
The collection of dried blood spots on filter paper offers a powerful tool in screening programs and...