Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect against infection or clear the persistent reservoir. Here, we have investigated the genetic and functional memory B cell and antibody landscape present during early infection in six individuals infected with either subtype A, C, or an A/C recombinant HIV-1. These individuals demonstrated varying levels of plasma autologous neutralization (nAb) against the transmitted/founder envelope (T/F Env) pseudovirus and non-neutralizing Fc-mediated effector function (nnFc) antibody-dependent cell-mediated cytotoxicity (ADCC) against the T/F Env gp120 protein at ~7 months after infection. Genetic analysis of the immunoglobulin heavy (VH) and light (VL) chai...
<div><p>The CD4 binding site (CD4BS) of the HIV-1 envelope glycoprotein (Env) contains epitopes for ...
Broadly neutralizing antibodies (bNAbs) have remarkable breadth and potency against most HIV-1 subty...
<div><p>HIV neutralizing antibodies (nAbs) represent an important tool in view of prophylactic and t...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Antibodies that neutralize (nAbs) genetically diverse HIV-1 strains have been recovered from a subse...
While the induction of broadly neutralizing antibodies (bNAbs) is a major goal of HIV vaccination st...
<div><p>While the induction of broadly neutralizing antibodies (bNAbs) is a major goal of HIV vaccin...
While the induction of broadly neutralizing antibodies (bNAbs) is a major goal of HIV vaccination st...
The CD4 binding site (CD4BS) of the HIV-1 envelope glycoprotein (Env) contains epitopes for broadly ...
<div><p>The CD4 binding site (CD4BS) of the HIV-1 envelope glycoprotein (Env) contains epitopes for ...
Broadly neutralizing antibodies (bNAbs) have remarkable breadth and potency against most HIV-1 subty...
<div><p>HIV neutralizing antibodies (nAbs) represent an important tool in view of prophylactic and t...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect aga...
Antibodies that neutralize (nAbs) genetically diverse HIV-1 strains have been recovered from a subse...
While the induction of broadly neutralizing antibodies (bNAbs) is a major goal of HIV vaccination st...
<div><p>While the induction of broadly neutralizing antibodies (bNAbs) is a major goal of HIV vaccin...
While the induction of broadly neutralizing antibodies (bNAbs) is a major goal of HIV vaccination st...
The CD4 binding site (CD4BS) of the HIV-1 envelope glycoprotein (Env) contains epitopes for broadly ...
<div><p>The CD4 binding site (CD4BS) of the HIV-1 envelope glycoprotein (Env) contains epitopes for ...
Broadly neutralizing antibodies (bNAbs) have remarkable breadth and potency against most HIV-1 subty...
<div><p>HIV neutralizing antibodies (nAbs) represent an important tool in view of prophylactic and t...