The expression of the parental proteins for MHC class I and II ligands and the whole proteome were depicted as RPKM (Reads Per Kilobase per Million mapped reads) of spleen mRNA levels determined using RNA-Seq. Similar to Figs 1 and 2, the four MHC ligand datasets included in this study were separately analyzed. The code color is: whole proteome (white bars), TAP+ (magenta bars), TAP-C (green bars), TAP-NC (orange bars), and HLA-II (black bars).</p
<p>Expression levels (LOG2 values of normalized protein abundance values) of cellular signaling prot...
Abstract Background Major histocompatibility complex class II (MHC-II) molecules present peptide fra...
Class I major histocompatibility complex (MHC) molecules assemble in the endoplasmic reticulum (ER) ...
Presentation of peptides on Major Histocompatibility Complex (MHC) molecules is the cornerstone in i...
Relative positions relative to the protein N-terminus for TAP+ (magenta bars), TAP-C (green bars), T...
Protein length (panel A), isoelectric point (panel B), hydrophobicity (GRAVY index) distribution (pa...
<p>(<b>A</b>) Enzymes involved in the ubiquitination of target proteins. (<b>B</b>) Subunits belongi...
Venn diagram showing absolute numbers of proteins shared between the different datasets analyzed: TA...
Abbreviations: major histocompatibility complex, MHC; soluble major histocompatibility complex molec...
MHC class II molecules are cell-surface glycoproteins that play a central role in the adaptive immun...
The highly polymorphic Major Histocompatibility Complex (MHC) genes are responsible for the binding ...
<p>Results of the peptide-a, b, c and d submitted to the IEDB T-cell MHC-II binding prediction serve...
A diagram of residues involved in the generation of naturally processed MHC ligands by peptidase cle...
<p>The cumulative distributions of the expression levels of mRNA probesets that were associated with...
The peptide repertoire that is presented by the set of HLA class I molecules of an individual is for...
<p>Expression levels (LOG2 values of normalized protein abundance values) of cellular signaling prot...
Abstract Background Major histocompatibility complex class II (MHC-II) molecules present peptide fra...
Class I major histocompatibility complex (MHC) molecules assemble in the endoplasmic reticulum (ER) ...
Presentation of peptides on Major Histocompatibility Complex (MHC) molecules is the cornerstone in i...
Relative positions relative to the protein N-terminus for TAP+ (magenta bars), TAP-C (green bars), T...
Protein length (panel A), isoelectric point (panel B), hydrophobicity (GRAVY index) distribution (pa...
<p>(<b>A</b>) Enzymes involved in the ubiquitination of target proteins. (<b>B</b>) Subunits belongi...
Venn diagram showing absolute numbers of proteins shared between the different datasets analyzed: TA...
Abbreviations: major histocompatibility complex, MHC; soluble major histocompatibility complex molec...
MHC class II molecules are cell-surface glycoproteins that play a central role in the adaptive immun...
The highly polymorphic Major Histocompatibility Complex (MHC) genes are responsible for the binding ...
<p>Results of the peptide-a, b, c and d submitted to the IEDB T-cell MHC-II binding prediction serve...
A diagram of residues involved in the generation of naturally processed MHC ligands by peptidase cle...
<p>The cumulative distributions of the expression levels of mRNA probesets that were associated with...
The peptide repertoire that is presented by the set of HLA class I molecules of an individual is for...
<p>Expression levels (LOG2 values of normalized protein abundance values) of cellular signaling prot...
Abstract Background Major histocompatibility complex class II (MHC-II) molecules present peptide fra...
Class I major histocompatibility complex (MHC) molecules assemble in the endoplasmic reticulum (ER) ...